Background: Vomiting after strabismus surgery is a common incidence and may induce many complications. Different drugs may be used as preventive steps.
Objective: To compare the effectiveness of droperidol and promethazine in prevention of vomiting following strabismus surgery.
Methods: Through an experimental research, 100 patients who were in the age range of 2 to 17 (ASA : 1) and candidated for strabismus surgery were randomly divided into two equal groups (50 cases).As anti-emetic drug, promethazine was infused (0.5 mg/kg/lm) to group A and droperidol (75 µg/kg/Iv) to group B , prior to the surgery. Both groups were followed up for 24 hours after surgery.X2 test was used for statistical comparison of two groups.
Findings: 7 patients (14%) in group A and 11 (22%) in group B had vomiting. No significant statistical difference was observed between two groups.
Conclusion: Promethazine is a good replacement for droperidolin prevention of vomiting, since deoperidol is a foreign product, expensive, may not always be available to anesthesiologists and can cause respiratory depression.