Nanoparticles of Mn0.5Zn0.5-xCdxFe2O4 with x varying from x=0.0 to 0.3 were prepared by wet chemical co-precipitation method. The structural and magnetic properties were studied by using X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), Transmission Electron Microscopy (TEM) and Electron Paramagnetic Resonance (EPR) technique. The lattice constant increases with increase in Cd content. This increase in the lattice constant is due to larger ionic radii of the Cd2+ (0.97 Ao) ions as compared to Fe3+ (0.64 Ao) ions. The intensities of the planes (220) and (440), increases with increasing Cd2+ion concentration. This shows that Cd2+ ions occupy tetrahedral A sites and octahedral B sites in the nano dimension against their chemical preference for A site. The line width (DHpp) and the g value of the Electron paramagnetic resonance (EPR) signal decreases with increase in the Cd content. The magnetic moment of all the samples up to x=0.2 calculated from EPR studies are lower when compared to the theoretical values. This lower value of magnetic moment confirms the existence of non collinear magnetic structure arising due to significant amount of spin disorder existing at B site.

Introduction: Acute renal failure is a common consequence of sepisis due to concurrent renal ischaemia. The role of nitric oxide (NO) in endotoxaemia and in ischaemic injury in the kidney is not well defined. Material and Methods: In this study we have used an animal model of sepsis induced by injection of bacterial lipopolysaccharide (LPS) in the rat and measured renal nitric oxide by X-band electron paramagnetic resonance (EPR) spectroscopy using the spin trap Fe2+-N-methyl-D-glucamine dithiocarbamate [Fe(MGD)2] given by intravenous injection 6 minutes before sacrifice. Results: The characteristic EPR spectrum of [Fe(NO)(MGD)2] was observed in kidneys of rats treated with LPS for 5h. Rat kidneys subjected to 20 min ischaemia and 5 min reperfusion had lower concentrations of [Fe(NO)(MGD)2] (1.0 ± 0.6 (M) compared to the contralateral nonischaemic kidneys (1.5 ± 0.9 (M, P<0.05). Conclusion: This study shows reduced levels of NO after renal ischaemia in vivo.