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Title

ANTIMICROBIAL ACTIVITY OF PIGMENTS EXTRACTED FROM RHODOTORULA GLUTINIS AGAINST SOME BACTERIA AND FUNGI

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Abstract

 Background: Nowadays hazards of synthetic additives and preservatives have been identified, so researchers are looking to a naturaland safe alternative for them. The aim of this study was to evaluate antimicrobial effect of carotenoids of Rhodotorula glutinison the some pathogenic bacteria and fungi.Methods: This experimental study was done in Gorgan University of Agriculture and Natural Resources. After cultivating R. glutinisin 50mLYPG broth at 30oC for overnight, cells were harvested by centrifugation at 10, 000rpmfor 10 minutes and were washed threetimes with distilled water. Cells were ruptured 3 times with 12 mL of acetone and broken using homogenizer. Then the suspensionwas centrifuged and the supernatant collected. The supernatant (contain pigments) was powdered using freeze-dryer. Antimicrobialactivity was evaluated by disc diffusion method and the minimum inhibitory concentration (MIC) and minimum bactericidalconcentration (MBC) was determined by using the agar dilution method.Results: Giving the results, carotenoids of R. glutinis was effective on the growth of all the tested bacteria, so that Bacillus cereusand Salmonella enteritidis were the lowest and highest sensitivity to this pigment, respectively. The highest MIC and MBC among thetested bacteria were observed for S. enteritidis and Escherichia coli, respectively; whereas MBC was not observed for S. enteritidis atconcentrations of the tested pigment.Conclusions: Gram-positive bacteria were more sensitive than Gram-negative bacteria against the antimicrobial activity of pigmentsof R. glutinis. According to the results, pigments of R. glutinis can be used as an inhibitor of bacterial growth.

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    APA: Copy

    YOLMEH, MAHMOUD. (2016). ANTIMICROBIAL ACTIVITY OF PIGMENTS EXTRACTED FROM RHODOTORULA GLUTINIS AGAINST SOME BACTERIA AND FUNGI. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 18(12), 0-0. SID. https://sid.ir/paper/703937/en

    Vancouver: Copy

    YOLMEH MAHMOUD. ANTIMICROBIAL ACTIVITY OF PIGMENTS EXTRACTED FROM RHODOTORULA GLUTINIS AGAINST SOME BACTERIA AND FUNGI. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2016;18(12):0-0. Available from: https://sid.ir/paper/703937/en

    IEEE: Copy

    MAHMOUD YOLMEH, “ANTIMICROBIAL ACTIVITY OF PIGMENTS EXTRACTED FROM RHODOTORULA GLUTINIS AGAINST SOME BACTERIA AND FUNGI,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 18, no. 12, pp. 0–0, 2016, [Online]. Available: https://sid.ir/paper/703937/en

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