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Information Journal Paper

Title

SHORT COMMUNICATION: TUBEROUS SCLEROSIS COMPLEX IN AUTISM

Pages

  408-411

Abstract

 Objective: To study the prevalence rate of tuberous sclerosis complex in autistic disorder.Methods: We studied one cohort of children followed up since 2005 until 2009, with autistic disorder, to determine the incidence of tuberous sclerosis complex. We established an autistic disorder registry in 2005 at China Rehabilitation Research Center. During the 4-year period (2005–2009), we collected a database of 429 children (390 boys and 39 girls; male to female ratio 10: 1) with autistic disorder and pervasive developmental disorders. We routinely examined all children with autistic disorder for any features of tuberous sclerosis complex by looking for neurocutaneous markers such as depigmented spots. In those with infantile spasm or epilepsy, the clinical features of tuberous sclerosis complex were monitored regularly during follow-up.Findings: Of these, five had tuberous sclerosis complex. Thus, the prevalence rate of tuberous sclerosis complex in autistic disorder is 1.17%. All of these children were mentally retarded with moderate to severe grades. Their IQ or developmental quotient was less than 70.Conclusion: The prevalence rate of tuberous sclerosis complex in autistic disorder was 1.17% in our region; autism spectrum disorder is a condition that might be associated with development of tuberous sclerosis complex.

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    APA: Copy

    GUO, XIN, TU, WEN JUN, & SHI, XIAO DONG. (2012). SHORT COMMUNICATION: TUBEROUS SCLEROSIS COMPLEX IN AUTISM. IRANIAN JOURNAL OF PEDIATRICS, 22(3), 408-411. SID. https://sid.ir/paper/579362/en

    Vancouver: Copy

    GUO XIN, TU WEN JUN, SHI XIAO DONG. SHORT COMMUNICATION: TUBEROUS SCLEROSIS COMPLEX IN AUTISM. IRANIAN JOURNAL OF PEDIATRICS[Internet]. 2012;22(3):408-411. Available from: https://sid.ir/paper/579362/en

    IEEE: Copy

    XIN GUO, WEN JUN TU, and XIAO DONG SHI, “SHORT COMMUNICATION: TUBEROUS SCLEROSIS COMPLEX IN AUTISM,” IRANIAN JOURNAL OF PEDIATRICS, vol. 22, no. 3, pp. 408–411, 2012, [Online]. Available: https://sid.ir/paper/579362/en

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