ASSESSMENT OF CLOPIDOGREL ON THE LEFT VENTRICULAR EJECTION FRACTION IN ACUTE MYOCARDIAL INFARCTION

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KHOSRAVI PEJMAN; SHEMIRANI HASAN; HEDAYATPOUR BEHNOUD; GOLABCHI ALLAHYAR

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Journal: International Journal of Preventive Medicine Year:2010 | Volume:1 | Issue:4 Page(s): 257-259

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Title

ASSESSMENT OF CLOPIDOGREL ON THE LEFT VENTRICULAR EJECTION FRACTION IN ACUTE MYOCARDIAL INFARCTION

Author(s)

KHOSRAVI PEJMAN | SHEMIRANI HASAN | HEDAYATPOUR BEHNOUD | GOLABCHI ALLAHYAR | Issue Writer Certificate

Keywords

HEART FAILURE

MYOCARDIAL INFARCTION

PREVENTION

Abstract

Objectives: Left ventricular (LV) dysfunction HEART FAILURE is one of the causes of morbidity and mortality following ST elevation MYOCARDIAL INFARCTION (STEMI). This study was done to determine the clopidogrel effect in preventing reduced LV function in patients with STEMI.Methods: In this study, 144 patients with STEMI admitted to the Isfahan University of Medical Sciences hospitals were followed in two groups for one month. The case group received Clopidogrel, 300 mg, on admission and then, 75 mg daily, while the control group received routine therapy for STEMI without Clopidogrel. Left ventricular ejection fraction (LVEF) on the 4th day and one month after STEMI was measured by echocardiography. The results of LVEF were compared within and between groups.Results: The mean LVEF in the case group on the 4th day and one month after STEMI were 45.92 and 52.15%, respectively (P<0.001). The mean LVEF in the control group on 4th day and one month after STEMI were 44.72 and 42.71%, respectively.Conclusions: We suggest that Clopidogrel is effective in PREVENTION of LVEF reduction in patients with STEMI.

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APA: Copy

KHOSRAVI, PEJMAN, SHEMIRANI, HASAN, HEDAYATPOUR, BEHNOUD, & GOLABCHI, ALLAHYAR. (2010). ASSESSMENT OF CLOPIDOGREL ON THE LEFT VENTRICULAR EJECTION FRACTION IN ACUTE MYOCARDIAL INFARCTION. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, 1(4), 257-259. SID. https://sid.ir/paper/315989/en

Vancouver: Copy

KHOSRAVI PEJMAN, SHEMIRANI HASAN, HEDAYATPOUR BEHNOUD, GOLABCHI ALLAHYAR. ASSESSMENT OF CLOPIDOGREL ON THE LEFT VENTRICULAR EJECTION FRACTION IN ACUTE MYOCARDIAL INFARCTION. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE[Internet]. 2010;1(4):257-259. Available from: https://sid.ir/paper/315989/en

IEEE: Copy

PEJMAN KHOSRAVI, HASAN SHEMIRANI, BEHNOUD HEDAYATPOUR, and ALLAHYAR GOLABCHI, “ASSESSMENT OF CLOPIDOGREL ON THE LEFT VENTRICULAR EJECTION FRACTION IN ACUTE MYOCARDIAL INFARCTION,” INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, vol. 1, no. 4, pp. 257–259, 2010, [Online]. Available: https://sid.ir/paper/315989/en

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