A Case-report of Concurrent Pulmonary and Cerebral Lesions in a Patient with Polymyositis: Invasive Aspergillosis or Astrocytoma?

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TEHRANI SHABNAM; YADEGARYNIA DAVOOD; KEYVANFAR AMIRREZA

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Journal Paper

Paper Information

Journal: Jundishapur Journal of Microbiology Year:2022 | Volume:15 | Issue:11 Page(s): 0-0

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Title

A Case-report of Concurrent Pulmonary and Cerebral Lesions in a Patient with Polymyositis: Invasive Aspergillosis or Astrocytoma?

Author(s)

TEHRANI SHABNAM | YADEGARYNIA DAVOOD | KEYVANFAR AMIRREZA | Issue Writer Certificate

Keywords

Aspergillosis

Astrocytoma

Invasive Pulmonary Aspergillosis

Polymyositis

Opportunistic Infections

Abstract

Introduction: Polymyositis is an idiopathic inflammatory myopathy that mainly manifests itself with muscle weakness. Patients with Polymyositis have a higher risk of developing infections and malignancies. We report concurrent pulmonary and cerebral lesions in a Polymyositis patient with many diagnostic challenges. Case Presentation: A 56-year-old woman complained of a productive cough and dyspnea from two weeks ago. Her symptoms gradually progressed until a sudden loss of consciousness occurred. She was a known case of Polymyositis and was treated with oral prednisolone. Imaging revealed concurrentpulmonaryandcerebral lesions. Initially, the patient underwent empirical therapy. However, the patient underwent a bronchoscopy because she did not respond to treatment. Specimens obtained from respiratory secretions revealed branched septate hyphae, and the culture was positive for Aspergillus fumigatus. She was diagnosed with invasive Aspergillosis, so we replaced the therapy with voriconazole. After three months, the lung lesions improved, but the number and extent of cerebral lesions increased. Finally, after a stereotactic biopsy, the patient was diagnosed with Astrocytoma and became a candidate for radiotherapy. Conclusions: Patients with Polymyositis are prone to contracting Opportunistic Infections and malignancies. Both of them can mimic each other and present diagnostic challenges to physicians. Thus, they should think about them for early diagnosis and timely treatment.

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APA: Copy

TEHRANI, SHABNAM, YADEGARYNIA, DAVOOD, & KEYVANFAR, AMIRREZA. (2022). A Case-report of Concurrent Pulmonary and Cerebral Lesions in a Patient with Polymyositis: Invasive Aspergillosis or Astrocytoma?. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), 15(11), 0-0. SID. https://sid.ir/paper/1079014/en

Vancouver: Copy

TEHRANI SHABNAM, YADEGARYNIA DAVOOD, KEYVANFAR AMIRREZA. A Case-report of Concurrent Pulmonary and Cerebral Lesions in a Patient with Polymyositis: Invasive Aspergillosis or Astrocytoma?. JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM)[Internet]. 2022;15(11):0-0. Available from: https://sid.ir/paper/1079014/en

IEEE: Copy

SHABNAM TEHRANI, DAVOOD YADEGARYNIA, and AMIRREZA KEYVANFAR, “A Case-report of Concurrent Pulmonary and Cerebral Lesions in a Patient with Polymyositis: Invasive Aspergillosis or Astrocytoma?,” JUNDISHAPUR JOURNAL OF MICROBIOLOGY (JJM), vol. 15, no. 11, pp. 0–0, 2022, [Online]. Available: https://sid.ir/paper/1079014/en

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