Objective: The article seeks to examine the cultural dimensions of the university entrepreneurship ecosystem. Culture in individual, organizational, educational, research, business and management dimensions are the drivers of social entrepreneurship development and its goal is to create social value. Method: The research is descriptive with survey technique and questionnaire tools. The statistical population is 44 university graduates who have worked in the field of social entrepreneurship. The sample size is selected by available sampling. Findings: Based on the findings, R2 values in the dimension of individual culture with (548. ), organizational culture with (555. ), educational culture with (508. ), research culture with (619. ), Business culture with (730. ) Explain the variance of the dependent variable with (619) management culture. Results: showed that the culture of university entrepreneurial ecosystem in different dimensions is the driver of social entrepreneurship development. Individual culture plays a role in the development of social entrepreneurship by motivating, strengthening self-confidence and identifying opportunities. Organizational culture with teamwork, planning and organizational citizenship behavior, educational culture with quality of education, teaching methods and appropriate educational content, managerial culture with accountability and criticism, business culture with risk-taking, creativity, opportunity and culture Research by quality of research Attention to technological research and knowledge-based (start-up) helps to develop social entrepreneurship, sense of responsibility and create social value.