Introduction: Inhalation induction is a common method in pediatrics anesthesia . There is not suitable clincial guide for assessmen depth of anesthesia before intubation, in this study adequacy of Jaw thrust as a guide for this assessement was evaluated.Methods: In a clinical trial study 90 pediatric patient, ASA1 & 2, six month to 5 year old age, were divided in case and control groups. Inhalation inductions were done by 4% Halothane, 4lit/min O2 and 4Lit/min N2o under spontaneous ventilation. In case and control groups, Jaw thrust and ordinary methods were utilized respectively for assessment of depth of anesthesia befor intubations. Changes in HR, SpO2, end tidal of halothane and duration of induction, duration of laryngoscopy, reactions to intubations and complications were measured and then analyzed by t - test and Chi squar statistical tests.Results: Duration and complications of larynogscopy were greater in case than control group. Conclusion: Jaw thrust alone is not a good clinical test assessment of depth of anesthesia before intubations in inhalation anesthesia. Probaly one and half to two minutes after negative respones to jaw thrust is a suitable time for intubations in pediatrics inhalation anesthesia .

Epidermoid cysts are benign, rare which can occur all throughout the body of an individual. Their occurrence in the oral cavity is rare and is difficult to distinguish from other intraoral cysts. A 27-year-old female patient presented with a swelling to the oral and maxillofacial surgery department for the removal of the cystic lesion. Based on the clinical and radiographic features the provisional diagnosis was given as odontogenic keratocyst. But the histopathological examination revealed a stratified squamous cystic epithelium with abundant keratin suggestive of an epidermoid cyst. This case report presents an uncommon finding in the oral cavity with a history of teeth extraction. Based on these findings even though epidermoid cyst is rare it should be included in the differential diagnosis of radiolucent lesions of the jaws.

Background: Dentigerous cyst and odontogenic keratocyte cyst are two common odontogenic developmental cysts. The different developmental mechanism and biological behaviour of odontogenic keratocyte cyst are due to intrinsic unknown factors in the epithelium or the enzymatic activity of its wall. P53 is involved in regulating the pathways of DNA rapier, apoptosis, angiogenesis, and maintaining genomic integrity, and is negatively regulated against Murine double minute 2. The aim of this study is to examine expression of Murine double minute 2 as an important marker of proliferation and regulation of cell cycle in odontogenic keratocyte cyst and Dentigerous cyst. Materials and Methods: In this descriptive-cross-sectional study, expression of Murine double minute 2 protein was explored in suprabasal and basal regions of epithelium of 15 specimens from each Dentigerous cyst and odontogenic keratocyte cyst via immunohistochemistry technique. Finally, the data were analysed by SPSS 22 and t-test and chi-square test. Results: expression of Murine double minute 2 in both suprabasal and basal regions in odontogenic keratocyte cyst was higher than Dentigerous cyst, but no significant relationship was obser ved (P: 0. 825) (P: 0. 551). The expression of this marker was significantly higher in the suprabasal region than basal region in both studied groups (P: 0. 005)(P: 0. 004). Conclusion: Higher expression of Murine double minute 2 in odontogenic keratocyte cyst can suggest the secondary role of this protein in the pathogenesis, growth, and development of this cyst and its different biological behaviour compared to other cysts.