Widespread antenatal screening has resulted to increased detection of anomalies of the kidneys and urinary tract.Fetal HYDRONEPHROSIS (dilatation of the renal pelvis with or without dilation of the renal calyces) is a common finding on antenatal ultrasound examination occurring in 0.5 to 1 percent of pregnancies. Although renal pelvic dilatation is a transient, physiologic state in most cases, urinary tract obstruction and vesicoureteral reflux (VUR) can occasionally be causal. These conditions can prevent normal renal development and/or cause renal injury.Management approach of infants with prenatal HYDRONEPHROSIS is based upon confirmation of persistent postnatal HYDRONEPHROSIS and the predicative factors such as: the severity of the HYDRONEPHROSIS, whether it is bilateral or unilateral, presence or absence of ureteral dilation, the history of amount of prenatal amniotic fluid volume, the presence of other findings in the urinary system, and whether progression occurs. Emergent factors are thinning of the parenchyma and/or cortical cysts which indicate injury or impaired development of the renal cortex. An echogenic renal cortex may mean renal dysplasia.Abnormalities of the bladder such as increased thickness and trabeculation of the bladder wall are consistent with obstructive uropathy distal to the bladder (eg, PUV).Postnatal follow-up includes ultrasound examination of the kidneys and bladder in all affected infants. For unilateral HYDRONEPHROSIS without antenatal bladder pathology, it performs at one week after birth. In infants with bilateral HYDRONEPHROSIS and those with a severe hydronephrotic solitary kidney, it performs within 48 hours of birth. Voiding cystourethrogram (VCUG) performs in unilateral or bilateral persistent HYDRONEPHROSIS, antenatally detected HYDRONEPHROSIS which develops a urinary tract infection, hydroureteronephrosis, dilated, thick-walled bladder and dilated posterior urethra. Diuretic renography (DTPA) performs in moderate to severe unilateral or bilateral HYDRONEPHROSIS which do not show VUR.