Introduction & Objective: Nowadays wound and its repair is important in its importance. Wound healing is a complex process that requires interaction between different types of cells, building proteins, growth factors and proteinases. Mast cell, fibroblasts and macrophages play an important role in wound healing. Recently, the use of ELECTROSPINING as a nanofiltration technology that can provide the same conditions as extracellular matrix can be used. Regarding the anti-bacterial properties of curcumin antioxidants for wound healing and the properties of polycaprolactone nano-fiber scaffolding by electrostatic method, the present study aimed to investigate the effect of this dressing on wounds in rat animal model. Materials & Methods: In this study, 48 male Sprague-Dawley rats weighing 300-350 g were used. The rats were randomly divided into 4 groups. After anesthesia, in the sterile condition, 1. 5 to 1. 5 cm in the back of the rat was formed. Then the dressing was done as Tie over in the first group PCL + curcumin 5%, the second group was PCL + curcumin 16%, in the third group pure PCL without curcumin and in the fourth group (control) with sterile gas dressing for up to 20 days. Dressing was changed every 5 days, and photos were photographed on 5, 10, 15, and the results of the photos were analyzed by image j software. On the 20th day, the samples were evaluated for histopathology. Results: The results of the difference in the mean of the wound surface between the four groups were significant only on the twentieth day (P = 0. 023). The results of the analysis between groups (two to two) showed that the difference in the trend between the first group to the second group (P = 0. 048), between the first and fourth groups (P = 0. 015) and between the second and fourth groups (P = 0. 029) and also between the third and fourth groups (P = 0. 031). There was no statistically significant difference in the overall score of pathology and pathological variables among the groups. Conclusions: The results show that loaded Curcumin ELECTROSPINING PCL scaffolds have good biocompatibility and have not shown any complications. This scaffold facilitates wound healing.

In this paper, synthesis of SnO2/ZnO composite hollow nanofibers using simple electrospinning method is reported. To improve the functional properties of composite hollow nanofibers, a different amount of ZnO precursor is added to the SnO2 precursor used in the solution. The structural and optical properties of produced nanofibers are studied using Scanning Electron Microscope (SEM), X-Ray (XRD) Diffraction, Ultraviolet-Visible Spectrophotometer (UV-Vis) and Fourier Transformed Infrared Spectrophotometer (FTIR). The XRD results show changes in the relative intensity of ZnO and SnO2 peaks with the increase or decrease amount of composite components. The FT-IR spectrum indicates a decrease in the relative band intensity of SnO2 with increasing ZnO in the composite. The UV-Vis spectra also show the flattening of the peaks by adding ZnO. Finally in the studying of photocatalytic properties with different ratios, the ratio of ZnO/SnO2 = 1/2 shows the highest color decomposition, of the order of 62%, in 2 hours under UV irradiation.

Introduction: Tissue engineering is the repair and replacement of damaged tissues and requires a combination of cells, growth factor and porous scaffolds. Scaffolds, as one of the main components in tissue engineering, are used as a template for tissue regeneration and induction and guidance of growth of the new and biologically active tissues. An ideal scaffold in tissue engineering, imitating an extracellular matrix, provides a suitable environment for adhesion, growth and cell proliferation. Scaffolds have also been used as the carriers for the controlled delivery of drugs and proteins. Variety of porous scaffolds, fabricated from biological and synthetic materials and using different manufacturing methods, have been introduced. Among them nanofibrous scaffolds have attracted great attention due to remarkable advantages including the highly porous three-dimensional structure with interconnected cavities which enable the transportation of food and waste materials, as well as high surface to volume ratio. So far, different methods and techniques have been introduced for production of scaffolds with structures similar to the extracellular matrix. Amongst them electrospinning, due to easiness and more control over effective parameters, are preferred. The present study make a review about the used materials and various methods of nanofibrous scaffold fabrication using electrospinning technology, with emphasis on the use of tissue engineering application. It also discussed about the progress and challenges ahead and the goals and perspective presented for this approach.

In recent years, the packaging industry has received a lot of attention due to the increasing demand of consumers to maintain quality and increase the shelf life of food products. These days, many food products lose their marketability due to poor storage and packaging conditions, which can lead to many losses. The electrospinning process by applying high electric field in polymer solution and forming nano fibers by suitable molecular properties and high surface area known as the common methods. In addition, nanofibers have received a lot of attention in food packaging due to the protection of quality and the promotion of protective properties. The usage of inorganic and metal nano particles as functional materials caused improvement of nanofiber properties in food packaging. In this study, the electrospinning process is introduced. Then, the usage of nanoparticles in food packaging are demonstrated. The usage of these nanoparticles has also been investigated to increase functional properties and improve the quality of food by using the electrospinning process.

Introduction: The field of tissue engineering utilizes interdisciplinary sciences such as to repair or regenerate damaged tissues through the integration of cellular biology, biomaterials, pharmaceuticals, and signaling molecules to repair and reconstruct damaged tissues. Scaffolds, by mimicking the natural extracellular matrix (ECM), play a vital role in guiding cellular activities. Cartilage, as a tissue without blood vessels and nerves, lacks the ability for self-repair, and its injuries are always considered a clinical challenge that affects the lives of millions of people and incurs significant treatment costs. In recent years, the electrospinning technique has gained attention for the production of nanofibers. Electrospun scaffolds, mimicking the extracellular matrix of cartilage, provide a suitable environment for the attachment, proliferation, and differentiation of chondrocytes. The use of nanofibrous scaffolds, along with cells and signaling molecules compatible with the target tissue, is of particular importance for cartilage tissue regeneration. Various natural and synthetic polymers have been used for cartilage tissue regeneration via electrospinning, and their effects on nanofiber morphology have been extensively studied. Conclusion: This review emphasized recent advancements in the preparation of electrospun scaffolds for cartilage tissue engineering and discussed methods to improve their performance. It also provides an overview of natural, synthetic, and composite biomaterials utilized for electrospinning cartilage scaffolds. The function of nanofibers in delivering signaling molecules for cartilage regeneration is explored. Current challenges in this field are addressed, along with strategies to overcome them, offering potential improvements in cartilage repair techniques and their future clinical application.