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Information Journal Paper

Title

Histopathologic Evaluation of Polymer Supports for Pintucci-type Keratoprostheses: An Animal Study

Pages

  243-250

Abstract

 Purpose: To report histopathological findings for different types of Polymers proposed as support for a Pintucci-type Keratoprosthesis. Methods: Six Polymers, including three types of polyesters (#1-3), one type of polytetrafluoroethylene (PTFE, #4), polyethylene (#5), and expanded polytetrafluoroethylene (ePTFE, #6) were evaluated. Four samples of each material were placed under the orbicularis oculi muscles of 12 rabbits. After five weeks, the samples were removed and evaluated histopathologically. Fibrovascular Tissue Ingrowths were investigated in terms of tissue penetration depth into the materials (graded as none, mild, moderate, and intense) and fibrovascular ingrowth area at the ultimate level of tissue penetrance. ImageJ software was used to calculate fibrovascular tissue area between the material fibers, and the mean area values were compared between the materials. Results: Polyester materials #1 and #3 demonstrated intense fibrovascular tissue penetration with a large fibrovascular ingrowth area,no overt tissue ingrowth was observed into material #6. The mean area of penetrated fibrovascular tissues was significantly different between materials (𝑃,< 0. 001). Materials #2, #4, and #5 showed moderate Fibrovascular Tissue Ingrowth and the area of presented fibrovascular tissue at the paracentral parts of material #4 was significantly smaller than that of materials #1 (𝑃,= 0. 02) and #3 (𝑃,= 0. 01). Conclusion: Two polyester materials that had relatively large pore sizes demonstrated a deep and large area of fibrovascular ingrowth. Given that material #3 is thicker and more consistent than material #1, the former can be used as the appropriate material for supporting the Pintucci-type Keratoprosthesis.

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    APA: Copy

    RAHMANI, SAEED, REZAEI KANAVI, MOZHGAN, JAVADI, MOHAMMAD ALI, Meskinfam Langroudi, Masoumeh, & Afsar Aski, Sasha. (2019). Histopathologic Evaluation of Polymer Supports for Pintucci-type Keratoprostheses: An Animal Study. JOURNAL OF OPHTHALMIC AND VISION RESEARCH, 14(3), 243-250. SID. https://sid.ir/paper/975271/en

    Vancouver: Copy

    RAHMANI SAEED, REZAEI KANAVI MOZHGAN, JAVADI MOHAMMAD ALI, Meskinfam Langroudi Masoumeh, Afsar Aski Sasha. Histopathologic Evaluation of Polymer Supports for Pintucci-type Keratoprostheses: An Animal Study. JOURNAL OF OPHTHALMIC AND VISION RESEARCH[Internet]. 2019;14(3):243-250. Available from: https://sid.ir/paper/975271/en

    IEEE: Copy

    SAEED RAHMANI, MOZHGAN REZAEI KANAVI, MOHAMMAD ALI JAVADI, Masoumeh Meskinfam Langroudi, and Sasha Afsar Aski, “Histopathologic Evaluation of Polymer Supports for Pintucci-type Keratoprostheses: An Animal Study,” JOURNAL OF OPHTHALMIC AND VISION RESEARCH, vol. 14, no. 3, pp. 243–250, 2019, [Online]. Available: https://sid.ir/paper/975271/en

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