Cellular Toxicity of Multi-walled Carbon Nanotubes on Human Lung Cells

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NASIRZADEH NAFISEH; RASOULZADEH YAHYA; REZAZADEH AZARI MANSOUR; MOHAMMADIAN YOUSEF

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Paper Information

Journal: JOURNAL OF CHEMICAL HEALTH RISKS Year:2020 | Volume:10 | Issue:2 Page(s): 135-144

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Title

Cellular Toxicity of Multi-walled Carbon Nanotubes on Human Lung Cells

Author(s)

NASIRZADEH NAFISEH | RASOULZADEH YAHYA | REZAZADEH AZARI MANSOUR | MOHAMMADIAN YOUSEF | Issue Writer Certificate

Keywords

Cytotoxicity

Carbon Nanotubes

IC50

NOAEC

A549 cells

Abstract

Nowadays, multi-walled carbon nanotubes (MWCNTs) are used in various industries. Considering the exposure probability of these nanomaterials to humans, the purpose of the present study is to assess the effect of MWCNTs on cellular toxicity of human alveolar epithelial. The A549 cells were cultured and treated to various doses of MWCNTs at three different times. Finally, the Tetrazolium colorimetric (MTT) assay was implemented for evaluating the cellular viability. The results indicated that the cytotoxicity for MWCNTs on the human alveolar epithelial cells is related to dose and time of exposure. The inhibitory concentration of 50% (IC50) and non-observed adverse effect concentration (NOAEC) are calculated to be 103. 6 as well as 0. 65μ g/mL, respectively. The findings of this present study could contribute to a better understanding of MWCNTs substances and might be useful as a basis for the future risk evaluation studies of exposed population in industries.

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APA: Copy

NASIRZADEH, NAFISEH, RASOULZADEH, YAHYA, REZAZADEH AZARI, MANSOUR, & MOHAMMADIAN, YOUSEF. (2020). Cellular Toxicity of Multi-walled Carbon Nanotubes on Human Lung Cells. JOURNAL OF CHEMICAL HEALTH RISKS (JCHR), 10(2), 135-144. SID. https://sid.ir/paper/772435/en

Vancouver: Copy

NASIRZADEH NAFISEH, RASOULZADEH YAHYA, REZAZADEH AZARI MANSOUR, MOHAMMADIAN YOUSEF. Cellular Toxicity of Multi-walled Carbon Nanotubes on Human Lung Cells. JOURNAL OF CHEMICAL HEALTH RISKS (JCHR)[Internet]. 2020;10(2):135-144. Available from: https://sid.ir/paper/772435/en

IEEE: Copy

NAFISEH NASIRZADEH, YAHYA RASOULZADEH, MANSOUR REZAZADEH AZARI, and YOUSEF MOHAMMADIAN, “Cellular Toxicity of Multi-walled Carbon Nanotubes on Human Lung Cells,” JOURNAL OF CHEMICAL HEALTH RISKS (JCHR), vol. 10, no. 2, pp. 135–144, 2020, [Online]. Available: https://sid.ir/paper/772435/en

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