MICROSCOPIC ENTERITIS, CLINICAL FEATURES AND CORRELATIONS WITH SYMPTOMS

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SHAHRAKI TOURAN; ROSTAMI KAMRAN; SHAHRAKI MANSOUR; BOLD JUSTINE; DANCIU MIHAI; AL DULAIMI DAVID; VILLANACCI VINCENZO; BASSOTTI GABRIO

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Journal: GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH Year:2012 | Volume:5 | Issue:3 Page(s): 146-154

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Title

MICROSCOPIC ENTERITIS, CLINICAL FEATURES AND CORRELATIONS WITH SYMPTOMS

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Keywords

COELIAC DISEASE

SEROLOGY

HISTOLOGY

MACROSCOPIC ENTERITIS

Abstract

Aim: To assess the clinical characteristic of CD as well as correlation of symptoms and the degrees of intestinal mucosal lesions in Iranian children.Background: Microscopic Enteritis (Marsh 0-II) is associated with malabsorption.Patients and methods: From August 2005 to September 2009, 111 cases with malabsorption and classical gastrointestinal symptoms were evaluated.Results: The mean (±SD) age of children with CD was 4.9±3.5 years (range, 6 month - 16 years) and the mean duration of symptoms was 8 ± 20.5 months.50 cases (45%) were female and 61 cases (55%) were male. The most common clinical presentation was failure to thrive in 72%, chronic diarrhea in 65.8% and Iron deficiency anemia in 59.5%. Sensitivity of EMA was 100% in patients with Marsh III b and Marsh III c. EMA was also positive in 77% of cases with Marsh 0, 18% in Marsh I, 44% in Marsh II and 81.8% in patients with Marsh III a.Conclusion: Histopathology did not reflect the severity of gluten sensitivity. This would suggest that the degree of intestinal mucosal damage might not be a reliable prognostic factor. Significant symptoms can be present with minor histological change on biopsy.

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APA: Copy

SHAHRAKI, TOURAN, ROSTAMI, KAMRAN, SHAHRAKI, MANSOUR, BOLD, JUSTINE, DANCIU, MIHAI, AL DULAIMI, DAVID, VILLANACCI, VINCENZO, & BASSOTTI, GABRIO. (2012). MICROSCOPIC ENTERITIS, CLINICAL FEATURES AND CORRELATIONS WITH SYMPTOMS. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, 5(3), 146-154. SID. https://sid.ir/paper/324554/en

Vancouver: Copy

SHAHRAKI TOURAN, ROSTAMI KAMRAN, SHAHRAKI MANSOUR, BOLD JUSTINE, DANCIU MIHAI, AL DULAIMI DAVID, VILLANACCI VINCENZO, BASSOTTI GABRIO. MICROSCOPIC ENTERITIS, CLINICAL FEATURES AND CORRELATIONS WITH SYMPTOMS. GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH[Internet]. 2012;5(3):146-154. Available from: https://sid.ir/paper/324554/en

IEEE: Copy

TOURAN SHAHRAKI, KAMRAN ROSTAMI, MANSOUR SHAHRAKI, JUSTINE BOLD, MIHAI DANCIU, DAVID AL DULAIMI, VINCENZO VILLANACCI, and GABRIO BASSOTTI, “MICROSCOPIC ENTERITIS, CLINICAL FEATURES AND CORRELATIONS WITH SYMPTOMS,” GASTROENTEROLOGY AND HEPATOLOGY FROM BED TO BENCH, vol. 5, no. 3, pp. 146–154, 2012, [Online]. Available: https://sid.ir/paper/324554/en

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