CA-125 IN NORMAL PREGNANCY AND THREATENED ABORTION

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AYATI SEDIGHEH; VAHID ROUDSARI FATEMEH; TAVASOLI F.

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Journal: International Journal of Reproductive BioMedicine Year:2007 | Volume:5 | Issue:2 Page(s): 57-60

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Title

CA-125 IN NORMAL PREGNANCY AND THREATENED ABORTION

Author(s)

AYATI SEDIGHEH | VAHID ROUDSARI FATEMEH | TAVASOLI F. | Issue Writer Certificate

Keywords

CA-125

PREGNANCY

ABORTION

THREATENED ABORTION

Abstract

Background: CA-125 is a glycoprotein and its origin is uncertain during PREGNANCY. It arises during the first trimester and return to a non-pregnancy range in late PREGNANCY.
Objective: The aim of this study was to compare CA-125 level in threatened ABORTION and normal PREGNANCY less than 20 weeks of PREGNANCY.
Materials and Methods: This was a prospective case study carried out on 50 healthy pregnant (group 1) and 50 threatened ABORTION women (group 2). We compared the levels of CA-125 in these groups and followed them to be informed of the outcome of PREGNANCY.
Results: Fifty percent of women were in 20-24 years old group, primigravida and in the first trimester of PREGNANCY. The mean level of CA-125 in group 1 was 26.2 ± 3.25 IU/ml and in group 2 was 37.44 ± 2.72 IU/ml. The mean level of CA-125 in finally aborted patients was 58.17±7.25 IU/ml and in normal pregnant women, who continue to term, was 26.61±1.76 IU/ml. The CA-125 level in threatened women, whose PREGNANCY continued and did not abort, was 30.89 IU/ml. There was statistically significant difference between mean serum CA-125 levels of two groups (p< 0.05), while there was no statistically significant difference between these levels in the patients of both groups who continued pregnancies (p> 0.1). In group 2, there was a statistically significant difference in the level of CA-125 between those who developed ABORTION and those whose PREGNANCY continued but not aborted (p< 0.05).
Conclusion: Measurement of serum CA-125 may be an inexpensive, easily available, sensitive and specific predictor of outcome in threatened ABORTION, which results the loss of PREGNANCY.

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APA: Copy

AYATI, SEDIGHEH, VAHID ROUDSARI, FATEMEH, & TAVASOLI, F.. (2007). CA-125 IN NORMAL PREGNANCY AND THREATENED ABORTION. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 5(2), 57-60. SID. https://sid.ir/paper/295116/en

Vancouver: Copy

AYATI SEDIGHEH, VAHID ROUDSARI FATEMEH, TAVASOLI F.. CA-125 IN NORMAL PREGNANCY AND THREATENED ABORTION. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2007;5(2):57-60. Available from: https://sid.ir/paper/295116/en

IEEE: Copy

SEDIGHEH AYATI, FATEMEH VAHID ROUDSARI, and F. TAVASOLI, “CA-125 IN NORMAL PREGNANCY AND THREATENED ABORTION,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 5, no. 2, pp. 57–60, 2007, [Online]. Available: https://sid.ir/paper/295116/en

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