DEVELOPMENT AND VALIDATION OF A TERBIUM-SENSITIZED LUMINESCENCEANALYTICAL METHOD FOR DEFERIPRONE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MANZOORI LASHKAR JAMSHID; AMJADI MOHAMMAD; SOLEYMANI JAFAR; TAMIZI ELNAZ; PANAHI AZAR VAHID; JOUYBAN ABOLGHASEM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH Year:2012 | Volume:11 | Issue:3 Page(s): 771-780

Download Full-Text

View:

339

Download:

158

Cites:

Information Journal Paper

Title

DEVELOPMENT AND VALIDATION OF A TERBIUM-SENSITIZED LUMINESCENCEANALYTICAL METHOD FOR DEFERIPRONE

Author(s)

Keywords

ANALYSIS

TERBIUM-SENSITIZED

DEFERIPRONE

TABLET

VALIDATION

Abstract

A sensitive fluorometric method for the determination of deferiprone (DFP) based on the formation of a luminescent complex with Tb3+ions in aqueous solutions is reported. The maximum excitation and emission wavelengths were 295 and 545 nm, respectively. The effects of various factors on the luminescence intensity of the system were investigated and optimized, then under the optimum conditions, the method was validated. The method validation results indicated that the relative intensity at 545 nm has a linear relationship with the concentration of DFP in aqueous solutions at the range of 7.2×10-9 to 1.4×10-5 M, the detection and quantification limits were calculated respectively as 6.3×10-9 and 2.1×10-8 M, precision and accuracy of the method were lower than 5% and the recovery was between 100.1% and 102.3%. The results indicated that this method was simple, time saving, specific, accurate and precise for the determination of DFP in aqueous solutions. After optimization and validation, the method successfully applied for determination of DFP in tablet dosage forms. The stoichiometry of the Tb3+-DFP complex was found as 1: 3 and the complex formation constant was 1.6×1016.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

MANZOORI LASHKAR, JAMSHID, AMJADI, MOHAMMAD, SOLEYMANI, JAFAR, TAMIZI, ELNAZ, PANAHI AZAR, VAHID, & JOUYBAN, ABOLGHASEM. (2012). DEVELOPMENT AND VALIDATION OF A TERBIUM-SENSITIZED LUMINESCENCEANALYTICAL METHOD FOR DEFERIPRONE. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), 11(3), 771-780. SID. https://sid.ir/paper/287983/en

Vancouver: Copy

MANZOORI LASHKAR JAMSHID, AMJADI MOHAMMAD, SOLEYMANI JAFAR, TAMIZI ELNAZ, PANAHI AZAR VAHID, JOUYBAN ABOLGHASEM. DEVELOPMENT AND VALIDATION OF A TERBIUM-SENSITIZED LUMINESCENCEANALYTICAL METHOD FOR DEFERIPRONE. IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR)[Internet]. 2012;11(3):771-780. Available from: https://sid.ir/paper/287983/en

IEEE: Copy

JAMSHID MANZOORI LASHKAR, MOHAMMAD AMJADI, JAFAR SOLEYMANI, ELNAZ TAMIZI, VAHID PANAHI AZAR, and ABOLGHASEM JOUYBAN, “DEVELOPMENT AND VALIDATION OF A TERBIUM-SENSITIZED LUMINESCENCEANALYTICAL METHOD FOR DEFERIPRONE,” IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR), vol. 11, no. 3, pp. 771–780, 2012, [Online]. Available: https://sid.ir/paper/287983/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops