FDG-PET/MRI FUSED DATA SETS FOR THE DETECTION OF LIVER METASTASES IN PATIENTS UNDERGOING SYSTEMIC ANTICANCER TREATMENT

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HEUSNER T.A.; MIKAT C.; HAHN S.; ALTENBERND J.; STAHL A.; BOCKISCH A.; FORSTING M.; ANTOCH G.

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Journal Paper

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Journal: International Journal of Radiation Research Year:2012 | Volume:9 | Issue:4 Page(s): 209-219

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Title

FDG-PET/MRI FUSED DATA SETS FOR THE DETECTION OF LIVER METASTASES IN PATIENTS UNDERGOING SYSTEMIC ANTICANCER TREATMENT

Author(s)

Keywords

PET/MRI

PET/CT

LIVER MRI

LIVER METASTASES

HYBRID IMAGING

Abstract

Background: To retrospectively describe imaging characteristics of LIVER METASTASES on fused FDG-PET/ MRI data sets and to compare the diagnostic accuracy of MRI and fused FDG-PET/MRI data sets for the detection of LIVER METASTASES in patients undergoing systemic anticancer treatment.Materials and Methods: 43 oncological patients (mean age: 56+/- 11 years) were investigated by FDG-PET/CT and LIVER MRI. FDG-PET data from PET/CT scans were fused with MRI. 556 lesions were evaluated. 5 different evaluation algorithms were used for FDG-PET/ MRI evaluation. The sensitivity, specifity, PPV, NPV and accuracy of MRI and FDG-PET/MRI data for the detection of LIVER METASTASES were calculated. A mean follow-up of 647 days served as reference standard. McNemar’s test was used to test for statistically significant differences between MRI and FDG-PET/MRI (p<0.5).Results: The sensitivity, specificity, PPV, NPV and accuracy of MRI for the detection of LIVER METASTASES were 86%, 81%, 97%, 47%, and 85% and 50%, 100%, 100%, 22%, and 56%, for FDGPET/ MRI. FDG-PET/MRI was significantly less accurate than MRI alone (p<.001).Conclusion: In opposite to patients before systemic anticancer therapy the fusion of FDG-PET data with LIVER MRI cannot be recommended for the detection of LIVER METASTASES in patients undergoing systemic oncological therapy.

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APA: Copy

HEUSNER, T.A., MIKAT, C., HAHN, S., ALTENBERND, J., STAHL, A., BOCKISCH, A., FORSTING, M., & ANTOCH, G.. (2012). FDG-PET/MRI FUSED DATA SETS FOR THE DETECTION OF LIVER METASTASES IN PATIENTS UNDERGOING SYSTEMIC ANTICANCER TREATMENT. INTERNATIONAL JOURNAL OF RADIATION RESEARCH, 9(4), 209-219. SID. https://sid.ir/paper/286566/en

Vancouver: Copy

HEUSNER T.A., MIKAT C., HAHN S., ALTENBERND J., STAHL A., BOCKISCH A., FORSTING M., ANTOCH G.. FDG-PET/MRI FUSED DATA SETS FOR THE DETECTION OF LIVER METASTASES IN PATIENTS UNDERGOING SYSTEMIC ANTICANCER TREATMENT. INTERNATIONAL JOURNAL OF RADIATION RESEARCH[Internet]. 2012;9(4):209-219. Available from: https://sid.ir/paper/286566/en

IEEE: Copy

T.A. HEUSNER, C. MIKAT, S. HAHN, J. ALTENBERND, A. STAHL, A. BOCKISCH, M. FORSTING, and G. ANTOCH, “FDG-PET/MRI FUSED DATA SETS FOR THE DETECTION OF LIVER METASTASES IN PATIENTS UNDERGOING SYSTEMIC ANTICANCER TREATMENT,” INTERNATIONAL JOURNAL OF RADIATION RESEARCH, vol. 9, no. 4, pp. 209–219, 2012, [Online]. Available: https://sid.ir/paper/286566/en

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