Relationship between seizures and metabolic acidosis: a prospective observational study

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Diler Yunus; Ozdemir Serdar; Altunok Ibrahim; Emre Eroglu Serkan

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Journal Paper

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Journal: Frontiers in Emergency Medicine Year:2022 | Volume:6 | Issue:2 Page(s): 0-0

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Title

Relationship between seizures and metabolic acidosis: a prospective observational study

Author(s)

Diler Yunus | Ozdemir Serdar | Altunok Ibrahim | Emre Eroglu Serkan | Issue Writer Certificate

Keywords

Acidosis

Epilepsy

Lactic Acid

Seizure

Abstract

Objective: To assess changes in blood gas parameters, such as pH, partial carbon dioxide pressure (PaCO2), bicarbonate (HCO3), base deficit, and lactate values, in patients who present to the emergency care unit after a Seizure. Methods: This is a prospective study on patients who suffered a generalized tonic-clonic Seizure. The demographic and biochemical data of the patients and their blood gas parameters were recorded both at the time of presentation to the emergency department and during the follow-up examination. Results: A total of 68 patientswere included in the study. Among the patients, 60. 3% (41)were male. The median age of the patients was 43 years (IQR: 29-65. 25). The median initial lactate value was 5. 7mmol/L (25th and 75th percentiles: 3. 5–, 8. 5 mmol/L). The median follow-up lactate value was 1. 8 mmol/L (25th and 75th percentiles: 1. 1–, 2. 8 mmol/L). The statistical analysis of the blood gas parameters revealed a statistically significant difference in the pH, PaCO2, base deficit, and lactate values between the initial and follow-up evaluations (P<0. 001). Conclusion: The results of our study suggest that metabolic Acidosis with high anion gap may develop due to the increase in the lactate levels as a result of a tonic-clonic Seizure.

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Cites

Relationship of Hospital Mortality with Metabolic Acidosis Severity in Critically Ill Patients

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APA: Copy

Diler, Yunus, Ozdemir, Serdar, Altunok, Ibrahim, & Emre Eroglu, Serkan. (2022). Relationship between seizures and metabolic acidosis: a prospective observational study. (FRONTIERS IN EMERGENCY MEDICINE) ADVANCED JOURNAL OF EMERGENCY MEDICINE, 6(2), 0-0. SID. https://sid.ir/paper/1137213/en

Vancouver: Copy

Diler Yunus, Ozdemir Serdar, Altunok Ibrahim, Emre Eroglu Serkan. Relationship between seizures and metabolic acidosis: a prospective observational study. (FRONTIERS IN EMERGENCY MEDICINE) ADVANCED JOURNAL OF EMERGENCY MEDICINE[Internet]. 2022;6(2):0-0. Available from: https://sid.ir/paper/1137213/en

IEEE: Copy

Yunus Diler, Serdar Ozdemir, Ibrahim Altunok, and Serkan Emre Eroglu, “Relationship between seizures and metabolic acidosis: a prospective observational study,” (FRONTIERS IN EMERGENCY MEDICINE) ADVANCED JOURNAL OF EMERGENCY MEDICINE, vol. 6, no. 2, pp. 0–0, 2022, [Online]. Available: https://sid.ir/paper/1137213/en

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