Screening Assessment of the Potential ‎Hazard of Nanomaterials using a Bull ‎Sperm

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Demetska O.; Beliuha O.; Movchan V.; Didenko M.; Riabovol V.; Patyka T.; Tsapko V.; Balia A.

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Journal Paper

Paper Information

Journal: International Journal of Nanoscience and Nanotechnology Year:2023 | Volume:19 | Issue:2 Page(s): 77-84

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Title

Screening Assessment of the Potential ‎Hazard of Nanomaterials using a Bull ‎Sperm

Author(s)

Keywords

Bull Sperm

Nanomaterials

Screening

Titanium dioxide.‎

Abstract

This paper studied a potential hazard of titanium dioxide Nanomaterials in the primary sreening methods on the sample of Bull Sperm. A method for stabilizing metal nanopowders and their derivatives for biomedical studies is proposed. It was found that the complex of titanium dioxide doped with silver (Ag-TiO2) and nanopowder of titanium dioxide (TiO2) at concentrations of 3 mg/ml initiate pathological changes in the Bull Sperm: the release of phospholipids as a result of the destruction of membranes and morphological abnormalities (abnormalities of the head, middle part, and tail, as well as the absence of acrosome, etc). The pathological effect of Ag-TiO2 nanocomposite was more pronounced. Doping with silver can increase the toxicity of nanotitanium dioxide, which requires further in-depth experimental studies using different concentrations by in vivo and in vitro methods.

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