The aim of this study was to study the role of mothers' perfectionism (adaptive and maladaptive) in their children's responsibility mediated by their academic self-efficacy. The research design was correlational. The statistical population included high school students in Yazd city and their mothers. Who was studying in the academic year 1400-1401. The study population was 16800 students. Morgan table was used to select the sample. A total of 342 female high school students and their mothers were selected by Multi-stage cluster random sampling method. The research instruments were the Hill Perfectionism Questionnaire (2004), the Self-Efficacy Questionnaire (1999) of Jings & Morgan, and Responsibility at Home and School Kordlow (2008). Path analysis using LISREL software showed a positive, direct and significant relationship between adaptive perfectionism and self-efficacy (r = 0. 405) and a positive, direct and significant relationship between adaptive perfectionism and responsibility subscale (r = 0. 453). There is. There is a positive, direct, and significant relationship between maladaptive perfectionism subscale and self-efficacy (r =-0. 102) and a negative, direct and significant relationship (r =-25. 25) between maladaptive perfectionism subscale and responsibility. There is a positive, direct, and significant relationship between self-efficacy and responsibility (r = 0. 378). Adaptive perfectionism has a positive, indirect, and significant relationship through the self-efficacy mediator variable of responsibility. Also, the correlation results for the subscales showed that striving for excellence, order and organization, purposefulness, as adaptive perfectionism, have a positive and significant relationship with self-efficacy, and high standards for others, interpersonal sensitivity as inconsistent perfectionism, negative and meaningful relationship with self-efficacy. have. Also, the results showed that striving for excellence, order and organization, purposefulness and high standards for others have a positive and significant relationship with responsibility and interpersonal sensitivity, perception of pressure by parents with responsibility, a negative and significant relationship. It is concluded that mothers' perfectionism is one of the effective factors on psychological and personality variables of children such as self-efficacy and responsibility. Therefore, the sensitive role of mothers in relation to children is reminded and education is recommended to mothers to increase awareness of the impact of maladaptive perfectionism on children's personalities.