Introduction: The aim of this study was to identify the relationship of attachment styles, marital satisfaction, and feeling of sex guilt with sexual desire in women. Method: Subjects were 192 married female students with the age range of 18-40 from University of Welfare Sciences and Rehabilitation, Tarbiat Modarres University and Islamic Azad University who participated in the present study by filling out the Adult Attachment Styles Index, ENRICH Marital Satisfaction Questionnaire, Mosher Revised Sex-Guilt Inventory and Hurlbert Index of Sexual Desire. Method of sampling was multistage clustering. Pearson correlation coefficient and regression analysis methods were used to analyze the data. Results: Findings showed that there is significant relationship between sexual desire with secure attachment style (r=0.283, p< 0.01), insecure avoidant attachment style (r=-0.321, p< 0.01), insecure ambivalent attachment style (r=0.144, p< 0.05), marital satisfaction (r=0.512, p< 0.01) and feeling of sex guilt (r=-0.442, p< 0.01). There was also significant negative relationship between sexual desire with age (r=-0.553, p< 0.01) and marital duration (r=-0.349, p< 0.01). Of all research variables, marital satisfaction, insecure ambivalent attachment style and feeling of sex guilt were able to predict 48.9 percent of the variance of sexual desire. Conclusion: Results of the present study show that those women with secure and ambivalent attachment styles and also higher levels of marital satisfaction, experience higher levels of sexual desire. On the other hand, women with avoidant attachment style, higher levels of feeling of sex guilt, older in age, and longer marital duration, experience lower levels of sexual desire.