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Issue Info: 
  • Year: 

    2013
  • Volume: 

    9
Measures: 
  • Views: 

    123
  • Downloads: 

    70
Abstract: 

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Yearly Impact:   مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 70
Issue Info: 
  • Year: 

    2014
  • Volume: 

    16
Measures: 
  • Views: 

    132
  • Downloads: 

    51
Keywords: 
Abstract: 

SYNTHESIS OF 2H-INDAZOLO [1,2-B] PHTHALAZINE-TRIONE DERIVATIVES, HAS EMERGED AS A POWERFUL TOOL IN ORGANIC SYNTHESIS DUE TO THEIR WIDE RANGE OF BIOLOGICAL ACTIVITIES SUCH AS CARDIOTONIC AND VASORELAXANT [1-3]. HETEROCYCLES CONTAINING THE PHTHALAZINE MOIETY ARE A CLASS OF COMPOUNDS, WHICH ARE HIGHLY RECOGNIZED IN THE FIELD OF MEDICINE AND ORGANIC CHEMISTRY DUE TO THEIR ANTIMICROBIAL, ANTICONVULSANT, ANTIFUNGAL , ANTICANCER AND ANTI-ANXIETY DRUG [4,5]. A NEW, SIMPLE AND EFFICIENT PROTOCOL IS USED FOR SYNTHESIS OF 2H-INDAZOLO [2,1-B] PHTHALAZINE TRIONES BY THREE COMPONENT CONDENSAION REACTION OF PHTHALHYDRAZIDE, AROMATIC ALDEHYDES AND CYCLIC DIKETONE (DIMEDONE) USING AL-SBA15/TPI/H6P2W18O62 UNDER SOLVENT-FREE CONDITIONS IN GOOD TO EXCELLENT YIELDS AND SHORT REACTION TIME .THE STRUCTURE OF THE PRODUCTS WERE CHARACTERIZED BY FURRIER TRANSFORM INFRARED SPECTROSCOPY (FT-IR). STABILITY, HIGHER ACIDITY AND ACTIVITY, AS WELL AS POWER METAL DISPERSION DUE TO THE HIGHER ACTIVITY OF THE CATALYST ARE ACHIVED BY EMPLOYING THIS NANO CATALYST. MOREOVER, THIS NANO CATALYST HAS EASY WORK UP UNDER HETEROGENEOUS CATALYTIC SYSTEMS WHICH INTENSIFY REACTION RATE AND ALSO CAUSES THE CATALYST TO BE SEPARATED EASILY FROM THE REACTION PRODUCTS, RECYCLED AND REUSED SEVERAL TIMES WITHOUT SIGNIFICANT LOSS OF ACTIVITY. THE STRUCTURE OF THE CATALYSTS (SIZE, SHAPE, SURFACE MORPHOLOGY) WERE CHARACTERIZED BY X-RAY DIFFRACTION (XRD) AND SCANNING ELECTRON MICROSCOPY (SEM).

Yearly Impact:   مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 132

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 51
Issue Info: 
  • Year: 

    2012
  • Volume: 

    18
  • Issue: 

    2
  • Pages: 

    103-118
Measures: 
  • Citations: 

    1
  • Views: 

    2487
  • Downloads: 

    0
Abstract: 

Objectives: Research in the development and application of the porous adsorbents with drug delivery capabilities is receiving great interest by the scientists. Porous adsorbents are able to improve bioavailability and solubility of drugs. They also are capable of controling the drug release for profound long-term implications in the pharmaceutical industry.Methods: The porous adsorbents which could be applied for pharmaceutical purposes together with the several methods of drug loading are explained in this review. The applications of the porous adsorbents in the pharmaceutical industry are explained as well.Results: Some of the commonly considered porous adsorbentse.g. SBA15, MCM41, MOFs and porous ceramic are reviewed in the current paper bearing in mind that these carriers could adsorb relatively high amounts of drugs and are able to improve drug release pattern.Conclusion: It is possible to formulate targeted drug delivery systems applying a suitable porous adsorbants.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 2487

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 1 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Issue Info: 
  • Year: 

    2020
  • Volume: 

    9
  • Issue: 

    2
  • Pages: 

    152-166
Measures: 
  • Citations: 

    0
  • Views: 

    195
  • Downloads: 

    0
Abstract: 

Background: Malachite green is a chemical pollutant and carcinogenic agent that is often used in some food and aquaculture industries to increase the production of aquatic products. Therefore, the removal of this pollutant before the discharge of the mentioned industrial wastewater in the aquatic environment is very important. The purpose of this study was to synthesize SBA-15 silica nanoadsorbent for the removal of cationic dye of malachite green from aqueous solutions and to investigate the kinetic and isotermic models, in order to built mathematical models for eliminating this pollutant dye. Methods: This experimental study was conducted on a laboratory scale. In this study, malachite green adsorption as a cationic color was studied on SBA-15 silica nano-adsorbent. The synthesis of this nano-adsorbent was carried out using the hydrothermal method. Data were presented in kinetic models of pseudo-first, second, Alovich, and intra-particle infiltration and isotherm models of Langmuir and Freundlich. FT-IR, XRD, and SEM were used to determine the characteristics of SBA15 nano-adsorbent. Results: The data at the time of equilibrium were highly consistent with the Langmuir isotherm model. The maximum removal rate was 98%, with an adsorbent amount of 0. 01 g/l, an initial concentration of 10 mg/l, pH=10, and contact time 120 minutes. Kinetic studies showed that the highest adsorption of malachite green followed the 2-hour contact time of the pseudo-second-order kinetic model, and intra-particle infiltration was also a speed controller. Conclusion: The results of this study showed that SBA-15 silica nano-adsorbent had high adsorption capacity for malachite green cationic dye and is recommended in the treatment of industrial wastewater with this colored pollutant.

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
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