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Journal: 

AQUATIC TOXICOLOGY

Issue Info: 
  • Year: 

    2006
  • Volume: 

    76
  • Issue: 

    2
  • Pages: 

    122-159
Measures: 
  • Citations: 

    1
  • Views: 

    309
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 309

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 1 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Issue Info: 
  • Year: 

    2000
  • Volume: 

    -
  • Issue: 

    4
  • Pages: 

    73-102
Measures: 
  • Citations: 

    1
  • Views: 

    239
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 239

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 1 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Issue Info: 
  • Year: 

    2014
  • Volume: 

    20
Measures: 
  • Views: 

    152
  • Downloads: 

    58
Keywords: 
Abstract: 

A NEW METHOD USING CHEMILUMINESCENCE (CL) DETECTION HAS BEEN DEVELOPED FOR THE, SIMPLE DETERMINATION OF KETOTIFEN DRUG. THE METHOD IS BASED ON THE CATALYTIC EFFECT OF KETOTIFEN ON THE CL REACTION OF TRIS (1, 10 PHENANTHROLINE) RUTHENIUM (II), [RU (PHEN)3 2+], WITH CE (IV) IN SULFURIC ACID MEDIUM [1]. THE CL RESPONSE WAS DETECTED USING A LAB MADE CHEMILUMINOMETER. EFFECTS OF CHEMICAL VARIABLES WERE INVESTIGATED SIMULTANEOUSLY USING AN EXPERIMENTAL DESIGN AND THE RESPONSE SURFACE METHODOLOGY (RSM). UNDER OPTIMUM CONDITIONS, THE CL INTENSITY WAS PROPORTIONAL TO THE CONCENTRATION OF THE DRUG IN SOLUTION OVER THE RANGE 0.34-34.00 MG ML-1.

Yearly Impact:   مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 152

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 58
Author(s): 

Journal: 

Curr Drug Saf

Issue Info: 
  • Year: 

    2023
  • Volume: 

    18
  • Issue: 

    4
  • Pages: 

    440-447
Measures: 
  • Citations: 

    1
  • Views: 

    5
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 5

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 1 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Writer: 

ARVAND M.

Issue Info: 
  • Year: 

    2012
  • Volume: 

    10
Measures: 
  • Views: 

    134
  • Downloads: 

    90
Keywords: 
Abstract: 

ANALYTICAL CHEMISTRY PLAYS A CRITICAL ROLE IN THE DEVELOPMENT OF A COMPOUND FROM ITS SYNTHESIS STAGE TO ITS MARKETING STAGE AS A PART OF A DRUG FORMULATION AND ANALYSIS. THE INSTRUMENTAL METHODS FOR QUANTITATION WHICH ARE MOST COMMONLY USED IN A PHARMACEUTICAL LABORATORY FALL INTO FOUR BASIC CATEGORIES: CHROMATOGRAPHY, SPECTROPHOTOMETRIC, ELECTROCHEMICAL, AND RADIOMETRIC ANALYSIS. ELECTROANALYTICAL CHEMISTRY HAD ITS ORIGINS EIGHT DECADES AGO. IT IS ONE OF THE FUNDAMENTAL SUBDISCIPLINES OF ANALYTICAL CHEMISTRY. IN THE LAST EIGHT DECADES, ELECTROCHEMICAL METHODS HAVE BECOME A POPULAR TOOL FOR THE STUDY OF ELECTROCHEMICAL REACTIONS AND DETERMINATION OF TRACE CONCENTRATIONS OF BIOLOGICAL AND CLINICALLY IMPORTANT COMPOUNDS.TILL NOW, THE COMMONLY EMPLOYED TECHNIQUES FOR THE DETERMINATION OF THE DRUGS ARE BASED ON HPLC, LC/MS, SPECTROSCOPY, AND MICROBIOLOGICAL ASSAYS. SUCH TECHNIQUES FOR THE MEASUREMENT OF BIOLOGICAL CONCENTRATION ARE NECESSARY IN A CLINICAL ENVIRONMENT TO ENSURE THAT ADEQUATE DRUG LEVELS CAN BE MAINTAINED WHILE AVOIDING TOXIC CONCENTRATIONS OF SUCH DRUGS. THE PROBLEMS ENCOUNTERED USING SUCH METHODS ARE EITHER THE NEED FOR DERIVATIZATION OR THE NEED FOR TIME-CONSUMING EXTRACTION PROCEDURES. SINCE THESE TECHNIQUES HAVE EXPENSIVE INSTRUMENTATION AND RUNNING COSTS, THE USE OF SIMPLER, FASTER, AND CHEAPER, YET SENSITIVE, ELECTROCHEMICAL TECHNIQUES CAN BE INTERESTING ALTERNATIVES, ESPECIALLY THOSE BASED ON ELECTROANALYTICAL TECHNIQUES.ELECTROCHEMISTRY HAS MANY ADVANTAGES, MAKING IT AN APPEALING CHOICE FOR PHARMACEUTICAL ANALYSIS.ELECTROCHEMISTRY HAS ALWAYS PROVIDED ANALYTICAL TECHNIQUES CHARACTERIZED BY INSTRUMENTAL SIMPLICITY, MODERATE COST, AND PORTABILITY. THESE TECHNIQUES HAVE INTRODUCED THE MOST PROMISING METHODS FOR SPECIFIC APPLICATIONS.

Yearly Impact:   مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 134

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 90
Author(s): 

Issue Info: 
  • Year: 

    2022
  • Volume: 

    25
  • Issue: 

    11
  • Pages: 

    1818-1837
Measures: 
  • Citations: 

    2
  • Views: 

    35
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 35

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 2 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Author(s): 

Issue Info: 
  • Year: 

    2022
  • Volume: 

    424
  • Issue: 

    -
  • Pages: 

    0-0
Measures: 
  • Citations: 

    1
  • Views: 

    8
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 8

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 1 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Author(s): 

MENDELSOHN R. | BALICK M.

Journal: 

ECONOMIC BOTANY

Issue Info: 
  • Year: 

    1995
  • Volume: 

    49
  • Issue: 

    -
  • Pages: 

    223-228
Measures: 
  • Citations: 

    1
  • Views: 

    175
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 175

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 1 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Author(s): 

Issue Info: 
  • Year: 

    2017
  • Volume: 

    3
  • Issue: 

    5
  • Pages: 

    60-74
Measures: 
  • Citations: 

    1
  • Views: 

    57
  • Downloads: 

    0
Keywords: 
Abstract: 

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 57

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesDownload 0 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesCitation 1 مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic ResourcesRefrence 0
Issue Info: 
  • Year: 

    621
  • Volume: 

    9
  • Issue: 

    1
  • Pages: 

    1-8
Measures: 
  • Citations: 

    0
  • Views: 

    9
  • Downloads: 

    0
Abstract: 

Research in medical sciences is vital for improving human health. Timely and accurate disease diagnosis is crucial for effective treatment and public health. Antigens and antibodies are essential for diagnostic testing, making their recombinant production important. Monoclonal antibodies have traditionally been produced using laboratory animals, but this method faces challenges, including the development of anti-mouse human antibodies. Phage display, a revolutionary technique that emerged in the 1980s, allows for the production of antibodies without laboratory animals, eliminating related concerns and enabling the selection of antibodies with optimal affinity for antigens. Phage display has numerous applications in medicine and PHARMACEUTICALS. It aids in the development of therapeutic antibodies for cancer, autoimmune disorders, and infectious diseases. By screening large libraries of antibodies quickly, researchers can identify effective treatment candidates. Additionally, phage display assists in vaccine development by identifying epitopes—specific parts of antigens recognized by the immune system—and plays a role in targeted drug delivery systems. This review emphasizes the transformative potential of phage display in diagnostics and therapeutics, highlighting its role in advancing health outcomes for all. HIGHLIGHTS Phage display allows for the production of antibodies without the use of laboratory animals. Phage display is used in developing therapeutic and vaccine design by identifying key epitopes. Phage display technology utilizes various bacteriophages, including M13, fd, f1, T7, T4, and lambda (λ).

Yearly Impact: مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View 9

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