The environmental pollution is a major problem for human kind. Water systems are usually confronting with the problems resulting from the different pollutants which kerosene and other oil products are very important material. The present study was under taken to study clinical and histopathological changes of exprimental Kerosene poisoning in gold fish (Carassius aurats).In this study 136 healthy gold fish were selected, and divided into a groups (One control and three experiment groups). Kerosene in amount of 10, 100, and 250ppm was added in to the water of groups 1,2 and 3 respectively. Duration of the trial was 21, day. Clinical signs in experiment groups included ataxia, anorexia. incresed mucus secretion, skin, ulcers and constipation. Fish of control showed no changes. Afetr necropsy and preparing the, tissue sections, from the gills, histopathological examination revealed hypermia, Hemorrhage, Infilteration of mononuclear in flammatory cells, fibrinous exudate and necrosis of Lamella in experiment groups but there lesions were more severe in fish of group 3.