Introduction: Intrauterine Growth Retardation (IUGR) is defined as approximate weight of embryo being less than the ten percentile. Some of the factors contributing to the IUGR are as follow: The mother history of chronic diseases, the mothers BMI, the trends of mother weight gain at the time of pregnancy, the mother’s age at the time of pregnancy, the mother’s job, various embryonic infections, placenta and uterine disorder. Materials and Methods: This cross-sectional, descriptive-analytical study was performed on pregnant women referring to the prenatal clinic of Baghiyatollah hospital at the years of 2009 and 2010 .Fifty hundred four pregnant women, between the age of 18 and 35 years were examined as available, these following variable were surveyed: The mother’s age at the time of delivery, the mother’s BMI at early pregnancy, the mother’s weight gain during pregnancy, the mother history of chronic diseases, the age of pregnancy, the mother’s job and education, blood group and RH, gravid, the interval of deliveries, gender of newborn with IUGR. Data was analyzed by SPSS, chi-square and the logistic regression model.'Results: 60.3% had normal BMI, 29.2% had BMI higher than normal, and 10.5% had BMI lower than normal. 50% had normal weight gain, 31.7% had weight gain higher than normal, 13.1% had weight again lower than normal, 10.3% had a chronic disease, 15.1% were employed and 83.3%of women were educated.There was a significant relationship among the mother’s BMI at the beginning of pregnancy, the rate of mother’s weight again during pregnancy, the mother’s history of chronic disease, the mother’s job and the newborn’s gender with IUGR. Conclusion: Probability of IUGR is higher in woman whose weight gain was lower than normal rang, female newborn and housekeeper mothers. There is a direct link between IUGR and the history of chronic disease in mothers.