Introduction: Impressive research demonstrates the importance of essential FATTY ACIDS for many physiological AND behavioral mechanisms in both human AND animals. Essential FATTY ACIDS must be supplied via the diet. In this study we assessed the dietary effects of CIS AND TRANS FATTY ACIDS on seizures induced by Pentylenetetrazol in rats.Materials AND Methods: In this study animals were divided into four groups. In the test groups CIS, TRANS or CIS AND TRANS FATTY ACIDS were add to the stANDard foods of rats AND in control group only stANDard food was dietary administrated. After one month kindling was established in rats with PTZ in subconvulsive dose (45mg/kg). Convulsing activities were monitored for 20 min. Results: Results showed that there was no meaningful difference between rat groups receiving CIS, TRANS or CIS AND TRANS FATTY ACIDS in their stANDard food.Conclusion: It was concluded that dietary administration of CIS AND TRANS FATTY ACIDS had no effect on Pentylenetetrazol kindling in rats.

Background & Aim: Impressive research demonstrates the importance of essential FATTY ACIDS for many physiological AND behavioral mechanisms in both humans AND animals. Experimental research showed that deficit in learning AND memory is induced after kindling. The objective of this study was to investigate whether dietary CIS AND TRANS FATTY ACIDS, pre AND during pentylenetetraxol (PTZ) kindling would effect learning deficits in male rats.Materials AND Methods: This is an experimental research. Eighteen Wistar rats were assigned in three groups. The control group received stANDard diet. The CIS AND TRANS groups received CIS AND TRANS FATTY ACIDS respectively. The kindling process was initiated one month after the start of the experiment, AND the shuttle box learning ability was assessd one week after kindling. Data were analyzed using one way ANOVA AND Tukey test. Results: Results showed control AND TRANS groups had impairment in shuttle box learning AND no considerable differences were found between these two groups. However on the other hAND administration of dietary CIS FATTY acid reduced impairment in shuttle box learning in pentylenetetrazol kindled rats.Conclusion: The results of this experiment suggest that dietary treatment of kindled rats with CIS FATTY ACIDS reduced learning deficits induced by PTZ kindling in rats.

Introduction: Gestational Diabetes Mellitus (GDM) is a common metabolic disorder in pregnancy that is diagnosed for the first time in the second half pregnancy. Associations between consumption of TRANS FATTY ACIDS AND GDM have been conflicted in many studies. The purpose of this study is to determine this relationship.Materials AND Methods: This is a narrative review to assess the relationship between TRANS FATTY ACIDS consumption before AND during pregnancy AND GDM incidence. We searched Google Scholar, Cochrane, AND Science Direct AND Med Line for identifying relevant analytic studies (Cohort AND case- control studies). We used the key words TRANS FATTY ACIDS, Gestational Diabetes Mellitus, pregnancy glucose intolerance.Result: At last we identified 12 relevant studies. Studies demonstrated that high TRANS FATTY ACIDS AND animal fat intake before AND during pregnancy significantly increased blood glucose levels in late pregnancy.Conclusion: High TRANS FATTY ACIDS intake AND animal fat consumption in daily diet before AND during pregnancy disturb glucose metabolism AND increase risk of GDM in the second half of pregnancy, although all of the studies recommended more widespread clinical trials to identify the exact relationship between high TRANS FATTY ACIDS intake AND GDM.