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Information Seminar Paper

Title

THE ANALYSIS OF HAPLOTYPE IN δβ THALASSEMIA DELETIONS

Pages

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Abstract

 BACKGROUND AND OBJECTIVES: BETA THALASSEMIA IS ONE OF THE MOST COMMON SINGLE-MUTATION DISEASES. THESE MUTATIONS CAUSE DECREASED BETA-GLOBIN PROTEIN SYNTHESIS OR EVEN DELETION. MOST OF MUTATIONS IN BETA-GLOBIN GENE ARE POINT MUTATIONS BUT THERE ARE SOME SMALL AND BIG DELETIONS IN BETA-GLOBIN GENE CLUSTER. THE AIM OF THIS STUDY WAS TO FIND THE RELATIONSHIP BETWEEN DB DELETIONS AND B-GLOBIN CLUSTER HAPLOTYPE. MATERIAL METHOD: GENOMIC DNA WAS EXTRACTED FROM 5ML OF PERIPHERAL BLOOD OF IRANIAN CARRIERS OF ΒTHALASSEMIA REFERRED FROM PRIMARY HEALTH CARE (PHC) CENTERS. THE HOMOLOGICAL DATA INDICATE THE LOW MCV AND LOW MCH VALUES AND NORMAL HBA2 AND HIGH HBF IN HETEROGENEOUS STATE. ...

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  • Cite

    APA: Copy

    Navab Moghadam, Fatemeh, Velaie, Atefe, BAYAT, FATEMEH, AHMADI, SETAREH, TAGHAVI, MARYAM, Mortezazadeh, Marjan, Kaini Moghadam, Zahra, Amiriyan, Azam, KORDAFSHARI, ALIREZA, KARIMIPOUR, MORTEZA, & ZEINALI, SIROUS. (2012). THE ANALYSIS OF HAPLOTYPE IN δβ THALASSEMIA DELETIONS. CONGRESS ON QUALITY IMPROVEMENT IN CLINICAL LABORATORIES (5TH INTERNATIONAL & 10 NATIONAL CONGRESS). SID. https://sid.ir/paper/930596/en

    Vancouver: Copy

    Navab Moghadam Fatemeh, Velaie Atefe, BAYAT FATEMEH, AHMADI SETAREH, TAGHAVI MARYAM, Mortezazadeh Marjan, Kaini Moghadam Zahra, Amiriyan Azam, KORDAFSHARI ALIREZA, KARIMIPOUR MORTEZA, ZEINALI SIROUS. THE ANALYSIS OF HAPLOTYPE IN δβ THALASSEMIA DELETIONS. 2012. Available from: https://sid.ir/paper/930596/en

    IEEE: Copy

    Fatemeh Navab Moghadam, Atefe Velaie, FATEMEH BAYAT, SETAREH AHMADI, MARYAM TAGHAVI, Marjan Mortezazadeh, Zahra Kaini Moghadam, Azam Amiriyan, ALIREZA KORDAFSHARI, MORTEZA KARIMIPOUR, and SIROUS ZEINALI, “THE ANALYSIS OF HAPLOTYPE IN δβ THALASSEMIA DELETIONS,” presented at the CONGRESS ON QUALITY IMPROVEMENT IN CLINICAL LABORATORIES (5TH INTERNATIONAL & 10 NATIONAL CONGRESS). 2012, [Online]. Available: https://sid.ir/paper/930596/en

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