ANTIANDROGENIC EFFECT OF ROSMARINUS OFFICINALIS EXTRACT IN MALE RAT

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AMERI F.; VAEZI GH.H.; GHAFARI MAREFAT NOVIN; HEYDARI MAHNAZ; KERAMATI KEYVAN

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Seminar Paper

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Seminar: IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY
Year:2007 | Issue:18

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Title

ANTIANDROGENIC EFFECT OF ROSMARINUS OFFICINALIS EXTRACT IN MALE RAT

Author(s)

AMERI F. | VAEZI GH.H. | GHAFARI MAREFAT NOVIN | HEYDARI MAHNAZ | KERAMATI KEYVAN

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Abstract

Introduction: Extracts of rosemary "Rosmarinus officinalis" have been used in folk medicine as a diuretic, an emenagogue an antispasmodic and abortive effect. The aim of this study was to evaluate the effect of rosemary extract on testosterone level in male rat.Methods and Material: The twenty four male Wistar rat were selected and randomly divided in control (n =8) and experimental (n=16) groups. The experimental groups split into two groups. The first and second experimental groups were received 50 and 100 mg/kg doses of rosemary aqueous extract made with leaves, flower and stem daily by gavage during 2 months period, respectively. However, the control group received only water. Blood samples were evaluated for testosterone level at 3 times before treatment, at mid period and the end of study by chemiluminescence.Result: The result of study showed that testosterone level had significant decrease in both experimental groups when compare to control group (P<0.05).Conclusion: It was concluded that rosemary extract have antiandrogenic effect.

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APA: Copy

AMERI, F., VAEZI, GH.H., GHAFARI MAREFAT, NOVIN, HEYDARI, MAHNAZ, & KERAMATI, KEYVAN. (2007). ANTIANDROGENIC EFFECT OF ROSMARINUS OFFICINALIS EXTRACT IN MALE RAT. IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. SID. https://sid.ir/paper/903311/en

Vancouver: Copy

AMERI F., VAEZI GH.H., GHAFARI MAREFAT NOVIN, HEYDARI MAHNAZ, KERAMATI KEYVAN. ANTIANDROGENIC EFFECT OF ROSMARINUS OFFICINALIS EXTRACT IN MALE RAT. 2007. Available from: https://sid.ir/paper/903311/en

IEEE: Copy

F. AMERI, GH.H. VAEZI, NOVIN GHAFARI MAREFAT, MAHNAZ HEYDARI, and KEYVAN KERAMATI, “ANTIANDROGENIC EFFECT OF ROSMARINUS OFFICINALIS EXTRACT IN MALE RAT,” presented at the IRANIAN CONGRESS OF PHYSIOLOGY AND PHARMACOLOGY. 2007, [Online]. Available: https://sid.ir/paper/903311/en

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