THE EFFECT OF CATECHIN ON FUNGAL BIOFILM FORMATION OF STANDARD SUSCEPTIBLE AND RESISTANT STRAINS OF CANDIDA ALBICANS

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HAGHIGHI F.; ROUDBAR MOHAMMADI SH.; FARHADI Z.

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Journal: Armaghane Danesh Year:2011 | Volume:16 | Issue:4 (64) Page(s): 332-340

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Title

THE EFFECT OF CATECHIN ON FUNGAL BIOFILM FORMATION OF STANDARD SUSCEPTIBLE AND RESISTANT STRAINS OF CANDIDA ALBICANS

Author(s)

HAGHIGHI F. | ROUDBAR MOHAMMADI SH. | FARHADI Z. | Issue Writer Certificate

Keywords

BIOFILMQ2

CANDIDAQ2

CATECHINQ2

Abstract

Background & Aim: CANDIDA albicans is the most common cause of fungal infections which is increasing all over the world. Finding new methods or agents for control of these fungal infections is necessary. The aim of this study was to evaluate the antifungal activity of CATECHIN against standard strain of C. albicans.Methods: This experimental study was conducted at Tarbiat Modares University of Medical Sciences in 2010. Serial dilutions of CATECHIN solution were prepared in 96 well micro plates. Minimum Inhibitory Concentration (MIC) was assessed by Microdilution broth technique. BIOFILMs of C. albicanswere developed on flat-bottomed 96-well microtiter plates and the antifungal effect of CATECHIN was evaluated. Data were analyzed using t-test statistical method.Results: MIC50 of 5.77 mg/ml, MIC90 of 8.33 mg/ml and MFC of 9.47 mg/ml were found for CATECHIN. BIOFILM inhibitory concentration of CATECHIN and fluconazole for susceptible strain of C. albicans was19.35, 4 mg/ml and for resistant strain was 23.53, 8 mg/ml respectively.Conclusion: CATECHIN had suitable antifungal effect against C. albicans BIOFILMs in comparison with fluconazole. It seems that this herbal agent can be used for the elimination of CANDIDA.

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Molecular study of Candida albicans isolated from periodontal infections and effect of Sargasum alga extract on biofilm ALS gene expression using Real-Time-PCR

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APA: Copy

HAGHIGHI, F., ROUDBAR MOHAMMADI, SH., & FARHADI, Z.. (2011). THE EFFECT OF CATECHIN ON FUNGAL BIOFILM FORMATION OF STANDARD SUSCEPTIBLE AND RESISTANT STRAINS OF CANDIDA ALBICANS. ARMAGHAN DANESH, 16(4 (64)), 332-340. SID. https://sid.ir/paper/78044/en

Vancouver: Copy

HAGHIGHI F., ROUDBAR MOHAMMADI SH., FARHADI Z.. THE EFFECT OF CATECHIN ON FUNGAL BIOFILM FORMATION OF STANDARD SUSCEPTIBLE AND RESISTANT STRAINS OF CANDIDA ALBICANS. ARMAGHAN DANESH[Internet]. 2011;16(4 (64)):332-340. Available from: https://sid.ir/paper/78044/en

IEEE: Copy

F. HAGHIGHI, SH. ROUDBAR MOHAMMADI, and Z. FARHADI, “THE EFFECT OF CATECHIN ON FUNGAL BIOFILM FORMATION OF STANDARD SUSCEPTIBLE AND RESISTANT STRAINS OF CANDIDA ALBICANS,” ARMAGHAN DANESH, vol. 16, no. 4 (64), pp. 332–340, 2011, [Online]. Available: https://sid.ir/paper/78044/en

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