Background and Aim: Recently some evidence has been presented that periodontal disease is associated with an increased risk of cardiovascular disease. The hypothesis of this study is that periodontitis may be associated with elevated blood lipid levels, a known risk factor for atherosclerotic disease. Methods & Materials: The levels of plasma lipids was measured in 40 subjects with chronic periodontitis (CP) and compared with those obtained in 40 controls. Periodontal variables included: Plaque Index (PU), Probing Pocket Depth (PPD), Clinical Attachment Level (CAL) and Bleeding On Probing (BOP). Laboratory tests included: total cholestrol, TRIGLYCERIDE, LDL and HDL. Statistical tests used were Kolmogorov-Smimov, Kruskal Wallis, Spearman's rank correlation, Exact fisher and Independent Samples Student t-test. The level of statistical significance was established at P£0.05.Results: There were no statistically significant differences between blood lipid levels in the two groups but in the control group, there were positive correlations between BOP and cholestrol (P=0.01). In the CP group there were positive correlations between PPD and cholestrol (P=0.037), PPD and LDL (P=0.034) and PPD and the number of missing teeth (P=0.019).There were also positive correlations between BOP and cholestrol (P=0.005) and BOP and LDL (P=0.006) in the CP group.Conclusion: The results of the present study suggest that in patients with periodontitis, as the periodontal parameters (BOP and PPD) increase, the blood levels of cholestrol and LDL increase too, but it is not clear yet whether the observed changes in lipid metabolism are the cause or the consequence of periodontitis.

Despite the fact that most people are worried about having high cholesterol levels, low cholesterol may actually be associated with adverse behavioral effects such as aggression and depression. The aim of this survey was to show whether there was a significant relationship between cholesterol and TRIGLYCERIDE with depression. The level of cholesterol and TRIGLYCERIDE was measured in 80 depressed patients referred or admitted to Sina hospital whose depressive symptoms were assessed by DSM IV criteria. The control group comprised of normal subjects. Cholesterol and TRIGLYCERIDE measurements were done on blood samples of the two groups. There was no significant relationship between age, sex and TRIGLYCERIDE levels with depression (P>0.05), but there was a significant relationship between low cholesterol and depression (P<0.05). It can be concluded that there is significant relationship between low cholesterol and depression whereas it is not the case for TRIGLYCERIDE