Chondromas are benign tumors that may be found in many parts of the body. Among intracranial neoplasms, tumors of cartilaginous origin are rare. It has been shown that most of these tumors arise from the skull base. Their occurrence in other parts of the intracranial cavity is unusual. Chondroma of FALX is a rare neoplasm. In this report we introduce a case of falcine chondroma arose from frontal midline area in a 17-year-old boy.

Chondroma is a benign tumor which mostly occurs in extremities but also sometimes in brain.Most intracranial chondromas arise from skull base, but chondroma of FALX origin is a rare circumstance.Indeed, the intracranial chondromas rise from FALX is mostly in relation with syndromic disorders such as Mafucci’s syndrome or Ollier’s syndrome. Here, we reported a rare case of FALXian intracranial chondroma in a young man who has normal physical examination and no signs of any syndromic disorder. The goal of this paper was to raise awareness about chondromas and suggest that chondroma be ruled out in any patient with masses arising from FALX.

Nevoid basal cell carcinoma syndrome (NBCCS) is a rare autosomal dominantly inherited condition in which constitutive pathway activity and tumor cell proliferation are disturbed due to defects in hedgehog signaling. This study reports an adult case of hemophilia A suspected of having Gorlin syndrome. There is no similar evidence in the literature to describe the association between these disorders. NBCCS is characterized by the development of multiple basal cell carcinomas (BCCs). The case presented in this study had two major manifestations of NBCCS, including the calcification of the FALX cerebri and the presence of keratocystic odontogenic tumors (KOTs); however, no minor manifestations of NBCCS were found in this case. On the other hand, given the financial restrictions, it was impossible to perform a genetic examination to confirm the presence of NBCCS.

Gorlin–Goltz syndrome is an autosomal dominant and a rare hereditary disease. Diagnosis of this syndrome is based on major and minor criteria. We report a Gorlin–Goltz syndrome in a 25-year-old male who was presented with progressive pain of maxilla and mandible over 5 years. The pain was diffuse and compatible with expansile cyst in alveolar ridges on panoramic radiography. In physical examination, he had coarse face and prognathism. Computer tomography of face revealed two expansile maxillary and one mandibular cyst. Calcification of entire length in FALX and tentorium were detected in bone window.

Nevoid basal cell carcinoma syndrome is a rare autosomal dominant disorder that usually characterized by multiple basal cell carcinomas, pits of the palms and soles, jaw cysts, intracranial calcification especially in FALX cerebri and skeletal abnormalities., In this case report a male patient is reported with a negative family history.

The nevoid basal cell carcinoma syndrome is a rare and autosomal dominant inherited disease with well-defined characteristics, summarized by Gorlin and Goltz in 1960. In the head and neck region, cerebral calcifications, Basal Cell Carcinoma (BCC) and multiple Odontogenic Kerato Cysts (OKC) of the jaws are the predominant findings. Odontogenic keratocysts with high rate of recurrency and basal cell carcinoma of the facial skin are important to dentists. In this article we present a 23 year old male with multiple recurrent cysts of the jaws who diagnosed to have Gorlin syndrome. The patient also has polydactily, palmar and plantar pits, bifid ribs, hypertelorism, calcification of FALX cerebri and missing of four wisdom teeth. Diagnosis, treatment and follow up of this case are discussed.

Gorlin-Goltz syndrome (GGS) consists of ectodermal and mesodermal abnormalities. In this case report we will investigate lower extremity lesions of GGS. A 52-year-old man with GGS underwent skull and lower extremity computer tomography. Radiographic findings included cervical spondylosis, transparent areas with slurred margins, and cerebral FALX calcification. Tibial and fibular specific cortical lesions (thin cortical and subcortical cystic lesions) were seen on the radiography, which was confirmed by computer tomography. To our knowledge, this is the first report of such a long lesion of the tibia and fibula. Specific lower extremity cortical lesions (thin cortical and subcortical cystic lesions) may occur and these abnormalities can be found on radiography or CT, which are most probably attributed to retinoid treatment.

Introduction: Gorlin syndrome is a rare disorder with different diagnostic criteria such as multiple odontogenic keratocysts, basal cell carcinomas, palmar&plantar pits, frontal bossing and hypertelorism and calcification of FALX cerebri.Case Report: The case which is reported in the present study was a 27-years old woman referred by a general dentist to oral medicine department of Hamadan dental faculty. On clinical and radiographic examination, multiple odontogenic keratocysts of jaws, multiple basal cell carcinomas, palmar pits and hypertelorism were obvious. The jaw cysts were treated with marsupialization and enucleation. The patient was referred to the dermatologist for photodynamic therapy.Conclusion: Most disorders of Gorlin syndrome are slight, which usually do not threat the patient’s life. The prognosis of this syndrome usually depends on the dermal tumor behavior.

Introduction: Nevoid BCC syndrome (Gorline syndrome) is a familial disorder with autosomal dominant inheritense. This syndrome is combination of multiple BCC that occurs at an early age, characteristic faces with: frontal bossing, broad nasal bridge and hypertelorism, jaw cysts, palmoplanter pitting, macrocephaly, skeletal and spinal anomalies include bifid ribes, cervical rib and kyphoscoliosis, CNS abnormality include corpus callusom disgenesia, FALX cerebri calcification (at early age) and mental deficiency.CaseReport: This case was a 25- years- old female presented with multiple and progressive skin lesions with different size in neck, upper trunk and axilla (multiple BCC), palmoplantar pitting, jaw cyst, cervical rib, bifid rib and liver haemangioma.Conclusion: With combination of clinical feature, histopathological reports of skin lesions and radiological reports of mandibular cyst and ribs anomalies, this case was diagnosed as nevoid BCC syndrome.