No abstract

Occupational commitment and organizational commitment are two types of commitment, which are investigated in this research. The organizational commitment is defined as an organization's goals acceptance, any effort regarding these goals and tendency to remain in the organization, and the occupational commitment is an identity determination based on an occupation, which includes commitment to the occupation, devoted to it and occupational goals and values acceptance. In this paper, a relationship between organizational commitment and occupational commitment is studied. The samples are 272 simple random selection based personnel of Isfahan Oil Refinery Center. Participants responded to the organizational commitment (Balfore & Wexler, 1996) and occupational commitment (Aranya, Pollock & Amernic, 1981) questionnaires. Stepwise regression was used for data analysis. The results showed that organizational commitment and any of its subscale (identification commitment, affiliation commitment, and exchange commitment) has a meaningful relation with occupational commitment at p£0.05.

The eukaryotic replisome is a multi-component complex that drives DNA replication with a speed of approximately 2 to 3 kb per min. This implies that chromatin is disrupted at a rate of around 10 to 15 nucleosomes every minute a head of each active replisome. To reproduce a similar chromatin environment on new DNA, histones and other chromatin-bound factors are transferred from the parental strand to the daughter strands. In addition, new histones are incorporated to maintain nucleosome density, and their modification signature should be assimilated to nearby old histones in the local chromatin environment. In general interaction between the components of the replisome and chromatin proteins can help to understand the proper way of improving the replication fork and its relationship to chromatin. In this study, the regulatory mechanism of chromatin replication and epigenome maintenance are evaluated.

The Varicella-Zoster Virus (VZV) genome contains both eis-acting and transacting elements, which are important in viral DNA replication. The eis-acting elements consist of two copies of oriS, and the trans-acting elements are those genes whose products are required for virus DNA replication. It has been shown that each of the seven genes required for ori-dependent DNA synthesis of Herpes Simplex Virus type-I (HSV) has a homologue in the VZV genome. However these seven genes of VZV never supp.orted replication of the plasmid containing VZV oriS, in the same assay. On the other hand, several laboratories have shown that co-transfected cosmid DNAs containing the overlapping VZV fragments can supply all of the necessary functions for the VZV virion development. In the present study we found that the four overlapping cosmids are as efficient as virion in supporting the in vitro replication of co-transfected plasmids containing oriS. On the basis of these results, subcloning of each of the cosmids used in this system should allow one to identify all of the VZV genes required for DNA replication in cultured cells.