THE APPLICATION OF CENTRALITY MEASURES IN BIOLOGICAL NETWORK ANALYSIS

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raeisi Vanani Sadegh; Razzaghi Moghadam Kashani Zahra; JAMALI YOUSEF

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Seminar Paper

Paper Information

Seminar: IRANIAN CONFERENCE ON BIOINFORMATICS
Year:2014 | Issue:5

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Title

THE APPLICATION OF CENTRALITY MEASURES IN BIOLOGICAL NETWORK ANALYSIS

Author(s)

raeisi Vanani Sadegh | Razzaghi Moghadam Kashani Zahra | JAMALI YOUSEF | Issue Writer Certificate

Keywords

BIOLOGICAL NETWORK ANALYSIS

NETWORK CENTRALITIES

GENE REGULATORY NETWORKS

PPI NETWORKS

Abstract

TOPOLOGICAL ANALYSIS OF BIOLOGICAL NETWORKS GIVES INSIGHTS INTO BIOLOGICAL PROCESSES. ONE OF THE USEFUL METHODSIN THIS FIELD IS THE NOTION OF CENTRALITY ANALYSIS THAT EVALUATES THE SIGNIFICANCE OF VERTICES WITHIN THE CONNECTION STRUCTURE OF THE NETWORK. IN THIS PAPER, DIFFERENT CONCEPTS OF CENTRALITY ON DIFFERENT TYPES OF BIOLOGICAL NETWORKSARE APPLIED TO CLARIFY THE MOST SIGNIFICANT ELEMENTS IN BIOLOGICAL PROCESSES. IT IS DEMONSTRATED THAT SOME DIFFERENT CENTRALITY MEASURES RESULT IN COMMON VALUATION OF THE VERTICES, WHILE SOME OTHERS MAKE DISTINGUISHED SIGNIFICANCES. ADDITIONALLY, A NEW CENTRALITY MEASURE CALLED K-PATH CENTRALITY IS APPLIED ON BIOLOGICAL NETWORKS. THE RESULTS INDICATETHAT THIS CENTRALITY CAN BE SUBSTITUTED FOR BETWEENNESS CENTRALITY AND FASTER EVALUATION WILL BE ACHIEVED.

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APA: Copy

raeisi Vanani, Sadegh, Razzaghi Moghadam Kashani, Zahra, & JAMALI, YOUSEF. (2014). THE APPLICATION OF CENTRALITY MEASURES IN BIOLOGICAL NETWORK ANALYSIS. IRANIAN CONFERENCE ON BIOINFORMATICS. SID. https://sid.ir/paper/929049/en

Vancouver: Copy

raeisi Vanani Sadegh, Razzaghi Moghadam Kashani Zahra, JAMALI YOUSEF. THE APPLICATION OF CENTRALITY MEASURES IN BIOLOGICAL NETWORK ANALYSIS. 2014. Available from: https://sid.ir/paper/929049/en

IEEE: Copy

Sadegh raeisi Vanani, Zahra Razzaghi Moghadam Kashani, and YOUSEF JAMALI, “THE APPLICATION OF CENTRALITY MEASURES IN BIOLOGICAL NETWORK ANALYSIS,” presented at the IRANIAN CONFERENCE ON BIOINFORMATICS. 2014, [Online]. Available: https://sid.ir/paper/929049/en

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