STANDARDIZATION CHALLENGES IN MEASURING TSH

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Bakhtiari Mohammad Reza

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Seminar Paper

Paper Information

Seminar: CONGRESS ON QUALITY IMPROVEMENT IN CLINICAL LABORATORIES
Year:2015 | Issue:13

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Title

STANDARDIZATION CHALLENGES IN MEASURING TSH

Author(s)

Bakhtiari Mohammad Reza | Issue Writer Certificate

Keywords

STANDARDIZATION

TSH

THYROID

Abstract

HUMAN THYROID STIMULATING HORMONE (HTSH) IS A 28-TO 30-KDAHETERODIMERICGLYCOSYLATED PEPTIDE SYNTHESIZED AND SECRETED FROM THYROTROPHS (BASOPHILE CELLS) OF THE ANTERIOR PITUITARY GLAND. ITS MAJOR ROLE IS TO REGULATE THE GROWTH AND FUNCTION OF THYROID GLAND. VARIATIONS IN N-TERMINAL OLIGOSACCHARIDE STRUCTURES OFBOTH ALPHA AND BETA SUBUNITS OF TSH GENERATE A MIXTURE OF CIRCULATING ISOFORMS (GLYCOFORMS), CHARACTERIZINGSOME OF THE PHYSIOLOGICAL HETEROGENEITIES OF THIS HORMONE, INCLUDING ITS HALF-LIFE IN BLOOD.THE PRECISE AND ACCURATE DETERMINATION OF TSH IN CLINICAL LABORATORIES IS OF GREATIMPORTANCE FOR PROPER DIAGNOSIS AND MANAGEMENT OF THYROID DYSFUNCTIONS.

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APA: Copy

Bakhtiari, Mohammad Reza. (2015). STANDARDIZATION CHALLENGES IN MEASURING TSH. CONGRESS ON QUALITY IMPROVEMENT IN CLINICAL LABORATORIES (8TH INTERNATIONAL & 13 NATIONAL CONGRESS). SID. https://sid.ir/paper/922447/en

Vancouver: Copy

Bakhtiari Mohammad Reza. STANDARDIZATION CHALLENGES IN MEASURING TSH. 2015. Available from: https://sid.ir/paper/922447/en

IEEE: Copy

Mohammad Reza Bakhtiari, “STANDARDIZATION CHALLENGES IN MEASURING TSH,” presented at the CONGRESS ON QUALITY IMPROVEMENT IN CLINICAL LABORATORIES (8TH INTERNATIONAL & 13 NATIONAL CONGRESS). 2015, [Online]. Available: https://sid.ir/paper/922447/en

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