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Title

THE SYNTHESIS OF COUMARIN DERIVATIVES USING CHOLINE CHLORIDE/ZINC CHLORIDE AS A DEEP EUTECTIC SOLVENT

Pages

  149-153

Abstract

 In this work, CHOLINE CHLORIDE/zinc chloride was employed as a DEEP EUTECTIC SOLVENT (DES) in the green synthesis of COUMARIN derivatives using Knoevenagel condensation. COUMARINs are important organic structures with useful application in various fields. The procedure consisted of the reaction between salicylaldehyde derivatives and active methylene compounds (dimethyl malonate, ethyl cyano acetate and ethyl 3-oxo-3-phenylpropanoate) to produce various COUMARIN derivatives. The general procedure is easy because of simple preparation and isolation of desired products. Moreover, the method is environmental friendly because of avoiding use of toxic solvents or hazardous CATALYSTs. In the presented method, only 10 % of CHOLINE CHLORIDE/zinc chloride was employed as a non-toxic and biologically degradable media. All reactions have been completed under mild conditions with high yields (61-96 %). The employed DES plays both roles of solvent and CATALYST in this reaction. Moreover, it has been reused four times in this procedure without important decreasing in the yield of reaction.

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    APA: Copy

    KESHAVARZIPOUR, FARIBA, & TAVAKOL, HOSSEIN. (2016). THE SYNTHESIS OF COUMARIN DERIVATIVES USING CHOLINE CHLORIDE/ZINC CHLORIDE AS A DEEP EUTECTIC SOLVENT. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS), 13(1), 149-153. SID. https://sid.ir/paper/283266/en

    Vancouver: Copy

    KESHAVARZIPOUR FARIBA, TAVAKOL HOSSEIN. THE SYNTHESIS OF COUMARIN DERIVATIVES USING CHOLINE CHLORIDE/ZINC CHLORIDE AS A DEEP EUTECTIC SOLVENT. JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS)[Internet]. 2016;13(1):149-153. Available from: https://sid.ir/paper/283266/en

    IEEE: Copy

    FARIBA KESHAVARZIPOUR, and HOSSEIN TAVAKOL, “THE SYNTHESIS OF COUMARIN DERIVATIVES USING CHOLINE CHLORIDE/ZINC CHLORIDE AS A DEEP EUTECTIC SOLVENT,” JOURNAL OF THE IRANIAN CHEMICAL SOCIETY(JICS), vol. 13, no. 1, pp. 149–153, 2016, [Online]. Available: https://sid.ir/paper/283266/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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