A Review of the Establishment of the Seed Lot System in the Production of Biological Products and Its Importance

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SOLEIMANI S.

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Journal Paper

Paper Information

Journal: Archives of Razi Institute Year:2022 | Volume:77 | Issue:6 Page(s): 2023-2035

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Information Journal Paper

Title

A Review of the Establishment of the Seed Lot System in the Production of Biological Products and Its Importance

Author(s)

SOLEIMANI S. | Issue Writer Certificate

Keywords

Vaccine

Seed

Lot

System

Characterization

Abstract

Today, due to the importance of diseases controlled by vaccination, the production of biological products is of great importance in ensuring public health, so producing high-quality biological products plays an important role in maintaining public health. One of the most important principles of manufacturing high-quality and efficient biological products is using suitable Seeds based on standard principles. To produce a suitable Seed for continuous use for mass production of biological products, the Seed must be defined according to certain principles and foundations. These principles are formed in the form of a Seed Lot System. In this review article, all the requirements for the establishment of a Seed to produce a biological product include general Seed information, including basic and Seed information and microorganisms, Seed-specific information including Seed passage levels, propagation method, Seed storage conditions, coding and labeling, identification information and design of suitable laboratories for passage, Seed propagation, and storage, determination of Seed characteristics including all necessary tests to determine Seed identity, purity, potency, efficacy, stability, safety and also all the necessary information for documenting and storing Seeds has been studied. Also, this study discusses the method of preparing all the necessary information for establishing a Seed Lot System, especially determining the characteristics of Seeds. Based on the study's results, a complete and comprehensive Seed Lot System has been formed that can be used to prepare, propagate, passage, and store Seeds used in the production of biological products.

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APA: Copy

SOLEIMANI, S.. (2022). A Review of the Establishment of the Seed Lot System in the Production of Biological Products and Its Importance. ARCHIVES OF RAZI INSTITUTE, 77(6), 2023-2035. SID. https://sid.ir/paper/1055522/en

Vancouver: Copy

SOLEIMANI S.. A Review of the Establishment of the Seed Lot System in the Production of Biological Products and Its Importance. ARCHIVES OF RAZI INSTITUTE[Internet]. 2022;77(6):2023-2035. Available from: https://sid.ir/paper/1055522/en

IEEE: Copy

S. SOLEIMANI, “A Review of the Establishment of the Seed Lot System in the Production of Biological Products and Its Importance,” ARCHIVES OF RAZI INSTITUTE, vol. 77, no. 6, pp. 2023–2035, 2022, [Online]. Available: https://sid.ir/paper/1055522/en

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