Introduction: Weirs are one of the most common hydraulic structures and are used to regulate the upstream approach flow depth, measure the flow discharge, and evacuate the excess flow discharge in dams, irrigation and drainage networks. Based on the ratio of the total head of the upstream approach flow to the length of the weir, weirs of finite crest length are categorized into four main groups, namely sharp-crested, short-crested, broad-crested, and long-crested type weirs. The thickness of the crest results in different velocity and pressure profiles over the weir crest and consequently tends to various flow behaviors. The shortcrested weirs are categorized as three different types, including ogee, circular-crested, and hydrofoil weirs. The hydrofoil weirs are a type of short-crested weirs that are designed on the basis of the airfoil theory. This kind of weirs has some merits compared to the other types, such as the high discharge coefficient, stability and submergence limit, and low fluctuations of pressure and water free-surface profile. Despite the extensive studies have been carried out on the hydraulic characteristics of the ogee and circular-crested weirs, there is a lack of comprehensive studies on the hydrofoil weirs, and therefore the flow characteristics over the hydrofoil weirs are still unknown. Methodology: A hydrofoil weir is designed, on the basis of the Joukowsky transformation function to the equation of a reference circle on the source coordinate plane. The weir pattern generated on the destination coordinate plane is a function of the radius and the coordinate of the center of the circle on the source coordinate plane. If the center of a circle in the source coordinate plane is offset just on the horizontal axis, the Joukowsky transformation yields a symmetric hydrofoil. In this situation, if the center of a circle in the source coordinate plane is offset as large as the radius of the reference circle, the Joukowsky transformation yields a circular-crested weir. On the other hand, if the center of the circle in the source coordinate plane is offset on both the horizontal-and vertical axis, the Joukowsky transformation yields an asymmetric hydrofoil. So far, only three published studies have examined the flow characteristics over symmetrical hydrofoil weirs. In symmetric hydrofoil weirs, the height of the weir is small, therefore these weirs have received less attention by the researchers till now. Whereas, by applying the asymmetric hydrofoil weirs instead of the symmetric ones, the weir height increases to be used for practical purposes. The present research subjects to study the flow behavior over the asymmetric hydrofoil weirs using experimental and numerical models. An experimental and numerical study was conducted, applying three and five models of the asymmetric hydrofoil weirs, respectively, designed on the basis of the Joukowsky transform function. Numerical simulations were performed using open source, OpenFoam v. 4. 0. 1, CFD software. The interFoam solver and the VOF (volume of fluid) method is used to achieve the water free surface profiles and the other hydrodynamic characteristics of the flow field. The PIMPLE (pressure implicit method for pressure linked equations) algorithm was applied to couple the pressure and velocity equations in two-phase flows. In the present study, structured meshes with hexahedral elements were created by the blockMesh utility of OpenFOAM software. To generate a finer grid mesh close to the weir body and along the water free surface, snappyHexMesh utility was applied. To validate the numerical results, former experimental results and the present experimental data of different hydrofoil weirs were applied. Based on the recommendations of former studies, the k-ω SST turbulence model was used for the determination of flow characteristics over the hydrofoil weirs. Results and discussion: The results of the numerical simulations including different geometrical characteristics, showed that the asymmetric hydrofoil weirs decrease the possibility of cavitation and the range of positive pressure downstream of the weir compared to those of circular-crested weirs, without decreasing the weir height. Also, in the asymmetric hydrofoil weirs, the results demonstrated that the greatest bed shear stresses and the compressive forces occur at the downstream end of the hydrofoil weir with a more camber, therefore, the downstream zone of these weirs is responsible for large values of bed erosion. Furthermore, the possibility of the downstream bed erosion is the same for the circular-crested weirs and the asymmetric hydrofoil weirs, having equal height. Conclusion: Finally, by applying asymmetric hydrofoil weirs instead of circular-crested weirs, unfavorable flow conditions would be removed, leading to a more safe and economic hydraulic structures, without decreasing the weir structural height.