Abstract. In this paper, we study the notion of semi-DERIVATION in Krasner hyperring and present some examples of them. We introduce the concept of generalized semi-DERIVATION in Krasner hyperring and present some examples. Then, we derive some properties of semi-DERIVATION on Krasner hyperring which proves the commutativity of a Krasner hyperring. Later we prove if f is a non-zero semi-DERIVATION on Krasner hyperring R, then f 2 6= 0 on R. Finally, for a generalized semi-DERIVATION F on R, if F(u ◦ v) = 0, for all u, v ∈ I, then R is commutative.