Islam in Iran, for nearly two centuries, Iranians did not have more political and administrative role. but with the rise of the Abbasids, opportunity influential Iranians impressive in eras of political and cultural. Iranian attituds to science and attention of caliphs to religious education conquered lands by Arabs, started the publication of religious sciences in Iran. Science first cause between Iranians to participate in Islamic government. Iranians in the formation of Islamic civilization and of course along with other nation played a significant contribution to the sharing of different nations. So, different regions according to the political situation in Iran including Ardabil cultural influence in the Islamic civilization. The author believes, by investigation the biographies of scholars Ardabil can be understood scientists Ardabil in the development of batch of sciences have involved, also strategic location and political events in the region and lack of dynamism and prosperity scientific centers of Ardabil has had an impact on the situation region of culture. The result indicates that the scientists most notably the activities of the Islamic sciences mysticism and Hadith involved. Also due to the political events and lack of dynamism scientific centers of area, many scientists outside the region.