Introduction. vesicoureteral reflux (VUR) has been known to be a risk factor for urinary system of infants and children with urinary tract infection. It can induce permanent adverse effect such as scar, hypertension, and ongoing declining renal function. DMSA renal scan is still a main pointer of acute and chronic damages of kidneys due to VUR. Other unsuccessful attempts including measuring interleukin-6 (IL-6), tumor necrosis factor (TNF)-alpha, and soluble TNF receptor-1 have been done to eliminate its invasive and expensive undesirable effect. The aim of this study was to determine and compare urine mean microalbumin and creatinie and their ratio between 3 groups of 2 to 10- year-old children affected by and recovered from reflux in comparion with normal matched age group. Methods. In this cross-sectional study, thirty-three 2- to 10-year children without UTI during the last 3 months, whose reflux or recovery had been diagnosed by VCUG or DRNC, were divided into 2 groups of 16 children affected by reflux, 17 recovered from reflux, and 18 matched normal children groups. Then, the point urine specimens were collected with permission of their parents in a single laboratory, and urine microalbumin (MA) and creatinine (Cr) for each specimen were measured. Alb/Cr ratio was calculated for each child to evaluate Alb excretion from urine possible without collecting 24-hours urine. MA/Cr ratio mean and MA were compared between the groups. To analyze our data, one way ANOVA test was used.Results. A total of 51 children, included 16 children affected by reflux, 17 recovered from reflux, and 18 normal children were entered to our study. The mean of MA/Crea and MA were 5.039±4.737 and 19.68±13.42 in affected group, respectively, 0.118 ± 0.187 in recovered group and 20.66 ± 12.5 in normal group. There was not a significant statistical difference between the 3 groups for MA and MA/Cr. Conclusion. Urine mean micro-albumin and its ratio with creatinine did not have any difference in children with reflux, with improved urinary reflux, and normal age matched group.