Aim: The present study aimed at surveying the relationship between spiritual quotient and human relationships among the principals of elementary schools of Esfarayen City in Iran.Methods: The sample group consisted of 100 randomly selected managers. Data gathering was carried out through spiritual quotient and human relationships’ tests. Descriptive statistics and the Pearson’s Correlation Coefficient were used for data analysis.Findings: The results showed that there was a significant and positive relationship between spiritual quotient and its elements including communication, self-awareness, trust, and motivation, on the one hand, and human relationships of the participants on the other. In addition, there was a positive and significant relationship between Transcendental Awareness, Conscious State Expansion, Personal Meaning Production, and Critical Existential Thinking, and human relationships among the participants.Conclusion: spirituality at work may result in increasing creativity, honesty, trust, sense of personal perfection, organizational commitment, job satisfaction, participation at work, morality and professional conscious, motivation, and performance. Therefore, a spiritual manager leads the organization toward success in a way that the customers, employees, and society members enjoy the benefits.