In this paper, we propose an efficient approach to design optimization of analog circuits that is based on the reinforcement learning method. In this work, Multi-Objective learning automata (MOLA) is used to design a two-stage CMOS operational amplifier (op-amp) in 0. 25μ m technology. The aim is optimizing power consumption and area so as to achieve minimum Total Optimality Index (TOI), as a new and comprehensive proposed criterion, and also meet different design specifications such as DC gain, Gain-Band Width product (GBW), Phase Margin (PM), Slew Rate (SR), Common Mode Rejection Ratio (CMRR), Power Supply Rejection Ratio (PSRR), etc. The proposed MOLA contains several automata and each automaton is responsible for searching one dimension. The workability of the proposed approach is evaluated in comparison with the most well-known category of intelligent meta-heuristic Multi-Objective Optimization (MOO) methods such as Particle Swarm Optimization (PSO), Inclined Planes system Optimization (IPO), Gray Wolf Optimization (GWO) and Non-dominated Sorting Genetic Algorithm II (NSGA-II). The performance of the proposed MOLA is demonstrated in finding optimal Pareto fronts with two criteria Overall Non-dominated Vector Generation (ONVG) and Spacing (SP). In simulations, for the desired application, it has been shown through Computer-Aided Design (CAD) tool that MOLA-based solutions produce better results.