The lecture will deal with Good laboratory Practice and laboratory Quality Control in general, but with special reference to IVF.Common sense and responsibility remain extremely important, but there are now special guidelines published by organisations like ESHRE, which can help ART units perform optimally.A quality management program consists of Quality Control, Quality Assurance and Quality Improvement. It is important to have a written quality policy highlighting the necessity of integration between the individual departments and functions like gynecology and embryology. Standard Operation Procedures (SOP) must be written and adhered to.Different aspects of laboratory QC, like biological specimens, patients, culture conditions, equipment, disposables etc., will be discussed. So will QA, like implantation rate, biochemical pregnancy rate, clinical pregnancy rate, baby-take-home rate, multiplet rate, survival rate after freeze-thaw etc.