The use of scientific methods to study and level the regions in terms of development in various economic, social, cultural, etc., has led to the recognition of inequality and a criterion for reducing and eliminating disparities among them. This article aims to investigate the status of socio-cultural, educational, economic, and health indicators in the cities of guilan province separately and in combination as well. It was a descriptive-analytical research, and the data collection method is library studies. To rank the cities of guilan province in terms of development of socio-cultural, educational, economic, and health indicators, the TOPSIS and Vikor leveling model and draw and prepare the maps the Geographic Information System (GIS) were used. Finally, an ANOVA test was used to analyze the variance between the two communities of Caspian coastal cities and other cities. The results showed that among the cities of guilan province, Bandar Anzali is the most developed city and Talesh is at the lowest level of development in combined indicators. Also, Bandar Anzali is the most developed in the economic indicators, and Rudsar is the most underdeveloped one. Finally, regarding the health indicators, Lahijan is the most developed, and Rezvanshahr is the least developed city of guilan province. Finally, the studies indicated the difference between coastal cities and other cities regarding development coefficient in the studied indicators.