Background & Purpose: Salt and pepper change is the retinal change that occurs in human retina and its cause is not entirely known. In the present study, the retina of patients infected with Giardia lamblia living in Tehran was examined for presence of "Salt and pepper" retinal change.
Methods& Patients: 50 girdiasis patients were selected as study group and 50 healthy individuals as control group. The retina of two groups was tested by ophthalmologist. White blood cells and eosinophila percentage were counted in haematology lab. For measurements of IgA and IgG Levels, SRID technique, and for IgE level, ELISA technique was applied.
Results & Conclusion: The results indicated, six patients of study group showed "Salt and pepper" retinal change in their eyes. When the patients treated with metronidazole, the ocular change disappeared in three of them. In addition, eosinophila percentage, IgA, IgE and IgG levels in the infected patients were found increased significantly in comparison with control group. Meanwhile, among patients with ocular change and without ocular change the differences of eosinophila percentage and IgE levels were found significant, According to IgA and IgG levels, no significant difference between two groups were observed.