Background: Health Expenditure is among the factors affecting the improvement of a society’ s health status. Hence, recognizing the effects of Public and private health Expenditure on health status is vital for making the required decisions. Objectives: This study aimed to compare the effects of different levels of health Expenditure on life expectancy, infant mortality rate, and under-five mortality rate as health indicators. Methods: The current study isananalytical research, whichwasconducted basedona cross-sectionalandannual time series data. In this study the effects of privateand Public health Expenditureonhealth indicators from2000to 2015 were investigated. The selected countries had the middle or high-income level and were classified into three groups based on the Public health Expenditure rate and k-mean method. The required data were collected from theWorld Bank site and for estimating the model, panel data regression models were used. Results: Public health Expenditure had a significant effect on health indicators in all groups, thus, an increase in Public health Expenditure led to increasing life expectancyand decrease infant andunder-five mortality rate in all groups. Also, the group with the highest share of health Expenditure had a greater impact on life expectancy and infant mortality, however, in regards to the underfive mortality rate, it was contrary. The effect of private health Expenditure was different and in most cases it had no significant effect. Conclusions: The findings of this study indicated that Public health Expenditure is more effective than the private health Expenditure and it also improved health status by creating positive external effects. Therefore, the governments must provide enough required financial resources for improving health status.