Guardianship is one of the most pivotal issues in Islamic mysticism, in light of which other basic ones such as Monotheism, Prophecy, and Mohammadyie are discussed. Mirza Aboulghasem-e Raz-e Shirazi, the Shiite mystic of 13th century, is amid those who have played a significant role in illustrating Guardianship debates. In the present study, first, the evolution of Guardianship studies in Islamic mysticism is discussed briefly and then, a short report of the works of this great mystic is provided. Then, the significance and the use of this debate in mysticism are discussed. After that, while studying the meaning of Guardianship, its various classifications and also, debates related to it such as monotheism, prophecy and truthfulness of Mohammadyie are dealt with. Following it, comes the "Intercommunication Principle" as the way to contact Guardianship holders and finally, spiritual relationship, which is the result of having relationship with Guardianship, is fleshed out.