Background and Objectve: Throat infections such as tonsilitis and pharyngitis in children can lead to absence from school, deferment from class, imposing treatment cost, and increasing the use of antibiotics. In addition to decreased mucosal salivary and mucosal immunity, smoking has harmful effects on oral microflora and may lead to tonsilitis. The aim of this study was to determine the effect of parents’ cigarette smoking on incidence of tonsillectomy in children referred to Kashani Hospital in Shahrekord during the period of 2017-2018. Subjects and Methods: This cross-sectional study was performed on children with tonsillitis who referred to ENT department of Rasool and Imam Ali Clinic Shahrekord Medical University. Eighty children aged 3 to 12 years old with tonsillitis and tonsillectomy indications were included in the study. Children age, gender and surgery type as well as information about their mother and father cigarette smoking habits were recorded. The data were analyzed by SPSS software using chisquare and logistic regression. Results: from 80 children, 42. 5% were male and 57. 5% were female. The mean age of children was 7. 30± 2. 26 y. The cases of adenoidectomy, tonsillectomy and adenotonsillectomy were 66. 3, 32. 5 and 1. 3%, respectively. 2. 5% of mothers of children and 45% of fathers of these children had cigarette smoking. From smokers’ father, 52. 8% had cigarette smoking in outdoors and 47. 2% had cigarette smoking indoor. There was no significant relationship between the type of surgery and status and place of cigarette smoking by mothers and fathers. Conclusion: Although there was no significant relationship between incidence of parents' cigarette smoking and tonsillectomy, the prevalence of cigarette smoking was relatively high among fathers of these children.