Introduction: Self-efficacy is the belief in one's ability and ability to perf(OR)m the task. One way to enhance employees' job self-efficacy is the manager's leadership style. The purpose of this study was to determine the c(OR)relation between leadership style of (OR):rgb(255,0,120);">Operating (OR):rgb(255,0,120);">room supervis(OR)s and (OR):rgb(255,0,120);">Operating (OR):rgb(255,0,120);">room technologists' selfefficacy in teaching hospitals of Iran University of Medical Sciences in 2017-2018. Methods: The present study is a descriptive-c(OR)relational study which was perf(OR)med on 220 (OR):rgb(255,0,120);">Operating (OR):rgb(255,0,120);">room technologists of hospitals of Iran University of Medical Sciences by stratified random sampling. Data were collected using two questionnaires: "Multifact(OR) Leadership Questionnaire" and "Job Self-Efficacy Questionnaire. " The content validity of the questionnaires was confirmed in previous studies, and their reliability was tested by the retest method. Data were analyzed using SPSS 21 software. Results: Most (OR):rgb(255,0,120);">Operating (OR):rgb(255,0,120);">room supervis(OR)s (65. 5%) had a transf(OR)mational leadership style. The maj(OR)ity of (OR):rgb(255,0,120);">Operating (OR):rgb(255,0,120);">room technologists (71. 4%) had high self-efficacy. There was a direct and significant c(OR)relation between transf(OR)mational, exchangeable, and non-interference leadership styles of (OR):rgb(255,0,120);">Operating (OR):rgb(255,0,120);">room supervis(OR)s with occupational self-efficacy (P < 0. 05). Also, the mean sc(OR)e of self-efficacy in transf(OR)mational and exchangeable leadership styles was higher than non-interventionist leadership styles. Conclusions: There is a direct relationship between job self-efficacy with all three types of leadership styles, but the mean sc(OR)e of self-efficacy in transf(OR)mational and exchangeable leadership styles is higher than the non-intervention style. Theref(OR)e, it is recommended that supervis(OR)s use transf(OR)mational (OR) transactional leadership styles, (OR) a combination of these two leadership styles, depending on the situation in the (OR):rgb(255,0,120);">Operating (OR):rgb(255,0,120);">room.