Context: Aberrometric analysis of thewavefront in patients with refractive disorders is performed using the ZERNIKE pyramidmode and based on that, a treatment plan is determined however, it is not clear what ZERNIKE modes are derived from mathematical analysis, exactly how much they correspond to the clinical facts this article discusses ways to study this issue. Evidence Acquisition: One of the methods for studying optical systems is the aberrometry of wavefront. the wavefront is a twodimensional surface perpendicular to a bunch of parallel light rays, that all these rays have the same phase on this surface (because light emits sinusoidally and therefore has multiple identical phases) whenever these rays pass through a refractive surface, it is also called the reference level this refractive index will be ideal if the homogeneity of these rays is maintained and the rays of this bunch of light will be able to focus at one point, but if the by passing light through the refractive surface thewavefront will be disturbedand the lights on this surface have different phases than the reference surface then it is said there is a discrepancy or deviation between the reference surface and thewavefront. Therefore, aberration is the creation of the distance of thewavefront in a certain phase from the refractive surface or reference surface. When we say refractive surface, we do not mean a specific place like the cornea because other than the cornea other factors such as crystalline lens, vitreous, retin even tear layer they are involved in creating aberrations, but usually the pupil range is considered as the reference surface. Results: Modes z-13 and z13 of the fourth order and modes z04 and z-24, z24 from the fifth order and modes z-15, z15 of six order and modes z06, z-26, z26 of seventh order they are not pure and mathematically they have some lower order whichmaycause in analysis aberrometry disruption as a result, the relevant orders have a little more or less value. Conclusions: There are no strong clinical reasons for ZERNIKE modes to be a fully accurate description of aberromerty, so clinicians should consider other clinical data and findings in their interpretation. Some modes of high-order ZERNIKE have sentences of loworder This can cause abnormal analysis.