ODONTOGENIC TUMORS contain a heterogeneous collection of lesions that are categorized from hamartomas to benign and malignant neoplasms of inconstant aggressiveness. ODONTOGENIC TUMORS are usually extraordinary with assessed frequency of short of 0.5 cases/100, 000 population for every year. The lesions such as ODONTOGENIC TUMORS are inferred from the components of the toothstructuring contraption. They are discovered solely inside the maxillary and mandibular bones. This audit speaks to experiences and cooperation of the molecular and genetic variations connected to the development and movement of ODONTOGENIC TUMORS which incorporate oncogenes, tumor‐silencer genes, APC gene, retinoblastoma genes, DNA repair genes, onco‐viruses, development components, telomerase, cell cycle controllers, apoptosis‐related elements, and regulators/controllers of tooth development. The reasonable and better understanding of the molecular components may prompt new ideas for their detection and administrating a better prognosis of ODONTOGENIC TUMORS.

Introduction: ODONTOGENIC TUMORS constitute an important aspect of oral and maxillofacial pathology. Frequency of ODONTOGENIC TUMORS varies in different societies but no study has been done in Zahedan so far. The purpose of this study was to achieve the sex, location and age distribution of ODONTOGENIC TUMORS and frequency of each one in a period of ten years.Materials & Methods: In this study, documents in archive of maxillofacial pathology department of Zahedan dental school, Khatamolanbia, Tamin ejtemaei Hospital and private laboratories were reviewed from 2000 to 2010. Data about age, sex, location of TUMORS and relation with impacted tooth were extracted and were submitted in the forms.Results: In this study, among the 1125 cases of the oromaxillofacial lesions, 50 cases of ODONTOGENIC TUMORS were found.Among the different TUMORS, keratocyst ODONTOGENIC tumor (KOT) was the most common ODONTOGENIC tumor (48%), followed by ameloblastoma and odontoma with frequency of 24% and 12%, respectively. There were no cases of malignancy. The incidence of these lesions was 52% in women and 48% in men. The most common location of TUMORS was posterior of mandible and TUMORS were more frequent in the third decade of life. In 12 cases, the lesions were accompanied by impacted teeth.Conclusion: In this study the most frequent TUMORS were KOT, Ameloblastoma and odontoma respectively.

Background and Aim: ODONTOGENIC cysts are divided into different types of developmental and inflammatory growth. ODONTOGENIC TUMORS comprise a complex group of lesions. The aim of this study was to evaluate the knowledge of general dentists working in Isfahan of common ODONTOGENIC cysts and TUMORS. Material and Methods: The statistical population of Isfahan general dentists and the number of samples was 199. Standard self-made questionnaires were used to assess the level of knowledge of dentists and paired analytical tests T and T and analysis of variance were used for statistical evaluations. Result: The mean score of knowledge about cysts (52. 9± 9. 8) and TUMORS (33. 8± 21. 6) was statistically significant, There was a significant difference between dentists' knowledge about cysts and TUMORS, Dentists were moderate for cysts and poor for TUMORS. Independent t-test showed that dentists' knowledge score about cysts and TUMORS was not significantly correlated with gender (P=0. 22, P=0. 21). One-way ANOVA showed that dentists' knowledge about cysts and TUMORS was not significantly correlated with the university of study (P=0. 73, P=0. 49), The results also showed that the mean score of dentists' knowledge was significantly correlated with the year of graduation (P = 0. 001, P = 0. 04)and the highest score was for graduates 69-80years and the lowest score was for graduates 86-90 years. Conclusion: The results showed that the level of knowledge of most dentists in Isfahan about cysts was moderate and that of TUMORS was poor. The mean score of dentists' knowledge about cysts was significantly higher than their knowledge of TUMORS was significantly correlated with the graduation year so older graduates were more aware about cysts and TUMORS.

Statement of Problem: ODONTOGENIC cysts and TUMORS are lesions that are found exclusively in the mandible and maxilla. These lesions are one of the main causes of jaw destruction. But unfortunately only a few studies have been conducted in Iran on relative frequency of these lesions.Purpose: The aim of this study was to determine the relative prevalence of ODONTOGENIC cysts and TUMORS in Kerman province along with age, sex and site of presentation over a 12-year period and to compare it with previous reports from different parts of the world.Materials and Method: This research reviewed 1320 biopsies in a 10 -year period. Data on factors such as age, sex and location of the lesions were extracted from pathology reports and analyzed by SPSS statistical software. Results: Of 1320 specimens, 221 were diagnosed as ODONTOGENIC cysts and 24 biopsies were diagnosed as ODONTOGENIC TUMORS. ODONTOGENIC cysts and TUMORS occurred most frequently in the first to second decades of life and most commonly in the mandible. Cysts were more common in men than women. Radicular cysts were the most common ones (33.9%), followed by dentigerous cysts (21.7%) and ODONTOGENIC keratocyst (15.4%). The most prevalent ODONTOGENIC tumor was ameloblastoma (41.4%).Conclusion: Our study provides demographic data on ODONTOGENIC cysts and TUMORS in Kerman province. ODONTOGENIC cysts have a predilection for certain ages, sexes and sites. To determine the real relative frequency of ODONTOGENIC TUMORS, further studies should be conducted, especially in Iran, by experienced pathologists in the field of ODONTOGENIC TUMORS.

Introduction: ODONTOGENIC cysts and TUMORS are associated with some lesions that impacted teeth are one of them. Impacted teeth are those cease to erupt before emergence.Varying incidences have been reported in different literature about this condition. The aim of this retrospective study was to achieve the sexual, location and age related distribution of ODONTOGENIC cysts and TUMORS and frequency of each one in relationship with an impacted tooth in order to prompt of clinician knowledge and easy selection of treatment plan.Materials and Methods: In this retrospective study, we used registration books and paraffinized blocks and slides of pathology archives of Mashhad dental school which had belonged to the patients involving with impacted teeth pathology, were evaluated from 1996- 2006.0ver all of these lesions were 304 cases in this period and relation between impaction of tooth and type of lesion was done by exact test.Results: This study included 160 lesions consisting of 140 cysts (87.5%) and 20 TUMORS (12.5%). Dentigerous cyst was the most common cyst (58.7%), and Odontoma was demonstrated to be the most commontumor (5%). These lesions affected males (59.8%) more than females (41.2%) and they occurred with a pick in the second decade. The left-sided posterior mandible was more commonly involved by far.Conclusion: The findings of this study for Dentigerous cyst and ODONTOGENIC keratocyst were similar to the findings of the other studies; nevertheless, Mandible and males predilection of Calcifying ODONTOGENIC cyst, one decade later involvement of Odontoma (3rd decade), one decade sooner involvement of Ameloblastoma (3rd decade), male predilection of Adenomatoid ODONTOGENIC tumor were not identical to the other studies, findings. However, more studies are recommended to achieve this purpose.

Introduction: Pigmented ODONTOGENIC lesions are rare,to date, only 60 cases have been reported in the literature. Melanocytes have been detected in a wide variety of ODONTOGENIC lesions. Several studies have discussed melanocyte presence and melanin production in ODONTOGENIC lesions, but its origin is still unclear. Therefore, the present systematic review aimed to gather information on such cases. Materials and Methods: An electronic search was performed in PubMed Cen-tral’, s database The search strategy was limited to human studies (case reports and case series) and full-text English articles published till June 2021. Irrelevant articles were omitted. Results: Pigmented ODONTOGENIC cysts (66. 66%) are more common than pigment-ed TUMORS. The most common pigmented cyst was calcifying ODONTOGENIC cysts (22 cases), followed by ODONTOGENIC keratocysts (10 cases). The most common pigmented neoplasm was mixed ODONTOGENIC TUMORS (10 cases). Pigmented lesions are more common in the Asian race. Conclusion: The melanocyte presence in ODONTOGENIC lesions has no particular prognostic importance. Some possible factors in this field include ethnicity, dental hard tissue induction, neural crest cells, and dental lamina’, s origin. Further documentation of such cases helps to improve the available information on these lesions.